Dr. David Sinclair

What you get with that is obviously not eating in bed, hopefully.

So you've got the night fast starting, what would it be, 7 p.m.

roughly?

When do you finish dinner?

Okay, but you've got at least 13, 14 hours, which is good.

Try to aim for 14 hours.

Some people go 16 hours, but that's a good start for fasting.

And hopefully you can do that most days, five days a week.

That's great because that means that you're turning on your sirtuins, raising your NAD.

You exercise as well, so that's also added into it.

One thing that I've started doing is fasting for longer than just 14, 16 hours.

I try maybe once a month to go for three days without eating.

Why?

Because there's a type of cellular recycling that doesn't happen within the first 16 hours.

You will enter ketosis, so your body will start to change its metabolism, produce what's called ketone bodies.

But the true, real, deep cleansing of old proteins and damaged proteins happens after two and a half to three days.

And it's called chaperone-mediated autophagy.

Autophagy is the word for auto-self-eating.

And it really kicks in with an extended fast.

Because your body doesn't want to do it.