Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

Dr. David Sinclair

๐Ÿ‘ค Speaker
2074 total appearances

Appearances Over Time

Podcast Appearances

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

And so now I rarely eat meat.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

I rarely drink alcohol.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

I focus on really fresh, high-quality food.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

preferably organic foods because I don't want pesticides and I don't want other contaminants.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

But I do know organic can be more expensive.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

Why not meat?

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So animals, unfortunately, don't make what are called polyphenols, which are a type of molecule that I believe and have evidence turns on the sirtuins and other pathways, biochemical reactions that delay ageing.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So sirtuins are just one of a few enzymes that control aging.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

We know this.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

There's sirtuins, there's mTOR, which responds to aminos, and another one called AMPK.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So those three pathways are altered in just the right way by molecules found only in plants.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

Well, and a small extent in fungi, but not in meat.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So if you're not eating a lot of vegetables or fruits, you're not getting these molecules.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

They're like medicine as food.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So right here, I hope you don't mind me mentioning that there is some food in front of us.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

And I'm looking at blueberries here.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

Blueberries are packed.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

with polyphenols one of the reasons they have purple color is that polyphenols have the color and as serena would tell you eat the rainbow i call it xenohormesis which is not as attractive but xenohormesis is the same idea as eat the rainbow that by eating plants that have a lot of these molecules that are often produced by stressed plants when you say stressed plants

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

So plants will be stressed just like we are.

The Diary Of A CEO with Steven Bartlett
David Sinclair: Can Aging Be Reversed?After 8 Weeks, Cells Appeared 75% Younger In Tests!

If you don't give them enough water, food, too much sunlight, not enough sunlight, in their defense, they make polyphenols.