Paul Turek

Yeah, so it's a shorter curve, but the same thing, 40, 38 to 40 is kind of a point where things really ramp up with chromosomes. The men's stuff is not chromosomal. If you take the curves together, they're different spans, same shape, but I think the female curve is on top of the male curve. This is not the same relative risk.

Yeah, so it's a shorter curve, but the same thing, 40, 38 to 40 is kind of a point where things really ramp up with chromosomes. The men's stuff is not chromosomal. If you take the curves together, they're different spans, same shape, but I think the female curve is on top of the male curve. This is not the same relative risk.

So women, you go from 25 to 40, your chance of a miscarriage, though it's chromosomal, it goes up quite significantly after that. Very significantly. And the consequence of women's issues with offspring related health is basically miscarriage.

So women, you go from 25 to 40, your chance of a miscarriage, though it's chromosomal, it goes up quite significantly after that. Very significantly. And the consequence of women's issues with offspring related health is basically miscarriage.

And now prevented with pre-imputation genetic testing. Men are different. You can't detect these things. They're single gene mutations. The machinery is constantly working. It's getting old. The quality control of the process goes down and little gene mutations get in there that are always being spun off in the heat of the engine. They're not getting vetted.

And now prevented with pre-imputation genetic testing. Men are different. You can't detect these things. They're single gene mutations. The machinery is constantly working. It's getting old. The quality control of the process goes down and little gene mutations get in there that are always being spun off in the heat of the engine. They're not getting vetted.

So the machinery is not doing a good job. So they're getting through and they're not going to be lethal. They're going to be deleterious. So that's where you get things. And autism is a classic one, paternal age related. Looks like that's the biggest risk factor for it. And that worries me a lot.

So the machinery is not doing a good job. So they're getting through and they're not going to be lethal. They're going to be deleterious. So that's where you get things. And autism is a classic one, paternal age related. Looks like that's the biggest risk factor for it. And that worries me a lot.

So the facts are that human evolution is entirely driven by sperm because eggs are just sitting there correcting the problem. It's entirely driven by sperm. And so 50 mutations a year, a generation usually gets spit out based on a nature paper. probably between generations. And there's always mutations occurring in 14-year-old fathers, but it goes way up with 60-year-old fathers.

So the facts are that human evolution is entirely driven by sperm because eggs are just sitting there correcting the problem. It's entirely driven by sperm. And so 50 mutations a year, a generation usually gets spit out based on a nature paper. probably between generations. And there's always mutations occurring in 14-year-old fathers, but it goes way up with 60-year-old fathers.

So the rate of mutations goes way up with age, but it averages 50 over a reproductive life. And most of them, half of the mutations that we are throwing off as a species are are not ears or hands or feet or height. It's all neurodevelopmental. It's like half neurodevelopmental.

So the rate of mutations goes way up with age, but it averages 50 over a reproductive life. And most of them, half of the mutations that we are throwing off as a species are are not ears or hands or feet or height. It's all neurodevelopmental. It's like half neurodevelopmental.

So when you think about what we're seeing, you know, the Martians from the fifties and the movies with big heads, that's kind of where we're headed. It's autism, dyslexia, bipolar disorder. These are neurodevelopmental neurodegenerative issues. And why is that? Well, that's what's going on. I mean, that's where we're being stimulated. That's where we're being asked to evolve.

So when you think about what we're seeing, you know, the Martians from the fifties and the movies with big heads, that's kind of where we're headed. It's autism, dyslexia, bipolar disorder. These are neurodevelopmental neurodegenerative issues. And why is that? Well, that's what's going on. I mean, that's where we're being stimulated. That's where we're being asked to evolve.

Look at the last 30 years. Funny. One of the biggest investors in Salesforce said to me, I realized I was dyslexic when my son was born. And I said, really? He said, yeah, but you know what? It helped me be the man I am to realize that Salesforce is going to fly. Gave him the first 500,000, gave him the first million, never took any more money. And he said, it let me focus.

Look at the last 30 years. Funny. One of the biggest investors in Salesforce said to me, I realized I was dyslexic when my son was born. And I said, really? He said, yeah, but you know what? It helped me be the man I am to realize that Salesforce is going to fly. Gave him the first 500,000, gave him the first million, never took any more money. And he said, it let me focus.

So autism is one of those diseases where you put out, you ignore a lot of input and And you find the gift and it's amazing. If you go down the rabbit hole of what they're good at, it's like their whole brain trust is there. So is that a disease or is that where we're headed?

So autism is one of those diseases where you put out, you ignore a lot of input and And you find the gift and it's amazing. If you go down the rabbit hole of what they're good at, it's like their whole brain trust is there. So is that a disease or is that where we're headed?

Maybe it's where we're headed. Maybe it's the future. Maybe the non-sequiturs that come out of those brains. Look at who's changing the world right now, at least in Silicon Valley.

Maybe it's where we're headed. Maybe it's the future. Maybe the non-sequiturs that come out of those brains. Look at who's changing the world right now, at least in Silicon Valley.