Annie Lowry
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Podcast Appearances
But it, like a lot of liver and kidney conditions, for reasons that are not understood at all, causes really, really bad itching that does not respond to antihistamines and does not respond to steroids.
But it, like a lot of liver and kidney conditions, for reasons that are not understood at all, causes really, really bad itching that does not respond to antihistamines and does not respond to steroids.
When scientists said that itching is a disease in and of itself, what they meant was was that chronic itching changes the body's own circuitry in a way that begets more chronic itching, that implies that itching is not just a side effect, it's a body process in and of itself.
When scientists said that itching is a disease in and of itself, what they meant was was that chronic itching changes the body's own circuitry in a way that begets more chronic itching, that implies that itching is not just a side effect, it's a body process in and of itself.
When scientists said that itching is a disease in and of itself, what they meant was was that chronic itching changes the body's own circuitry in a way that begets more chronic itching, that implies that itching is not just a side effect, it's a body process in and of itself.
And so instead of just being a symptom, instead of being something where if you fix the underlying issue, you might fix the itch, itch itself can kind of rewire the body and can be treated as a condition unto itself. And a lot of dermatologists see itch that way. It's often a symptom, often a side effect, but sometimes it's really its own thing in the body.
And so instead of just being a symptom, instead of being something where if you fix the underlying issue, you might fix the itch, itch itself can kind of rewire the body and can be treated as a condition unto itself. And a lot of dermatologists see itch that way. It's often a symptom, often a side effect, but sometimes it's really its own thing in the body.
And so instead of just being a symptom, instead of being something where if you fix the underlying issue, you might fix the itch, itch itself can kind of rewire the body and can be treated as a condition unto itself. And a lot of dermatologists see itch that way. It's often a symptom, often a side effect, but sometimes it's really its own thing in the body.
It's a great question, and I think that the answer is multilayered. So one is that doctors didn't understand itch, even just that basic histaminergic itch, very well until recently. There's not a lot of drugs to treat itch, and there didn't seem to be a lot of money in treating itch. there's a lot of money in treating pain, right?
It's a great question, and I think that the answer is multilayered. So one is that doctors didn't understand itch, even just that basic histaminergic itch, very well until recently. There's not a lot of drugs to treat itch, and there didn't seem to be a lot of money in treating itch. there's a lot of money in treating pain, right?
It's a great question, and I think that the answer is multilayered. So one is that doctors didn't understand itch, even just that basic histaminergic itch, very well until recently. There's not a lot of drugs to treat itch, and there didn't seem to be a lot of money in treating itch. there's a lot of money in treating pain, right?
An upsetting amount of money that has led to a tremendous social crisis due to our treatment of pain. But it is also true that, you know, there's a lot of chronic pain and we have a lot of ways to treat it. And, you know, I think there's now a lot more emphasis on non-opiate medications to treat pain while also acknowledging that a appropriate opiate medications to treat pain.
An upsetting amount of money that has led to a tremendous social crisis due to our treatment of pain. But it is also true that, you know, there's a lot of chronic pain and we have a lot of ways to treat it. And, you know, I think there's now a lot more emphasis on non-opiate medications to treat pain while also acknowledging that a appropriate opiate medications to treat pain.
An upsetting amount of money that has led to a tremendous social crisis due to our treatment of pain. But it is also true that, you know, there's a lot of chronic pain and we have a lot of ways to treat it. And, you know, I think there's now a lot more emphasis on non-opiate medications to treat pain while also acknowledging that a appropriate opiate medications to treat pain.
So there just wasn't a lot of optionality for treating itch. It wasn't the sort of thing that medical centers were going to make a lot of money by treating people with chronic itch because they didn't have options to give them. I also think that there's a social aspect. Pain is so awful. And I would never say that there's something ennobling about pain.
So there just wasn't a lot of optionality for treating itch. It wasn't the sort of thing that medical centers were going to make a lot of money by treating people with chronic itch because they didn't have options to give them. I also think that there's a social aspect. Pain is so awful. And I would never say that there's something ennobling about pain.
So there just wasn't a lot of optionality for treating itch. It wasn't the sort of thing that medical centers were going to make a lot of money by treating people with chronic itch because they didn't have options to give them. I also think that there's a social aspect. Pain is so awful. And I would never say that there's something ennobling about pain.
But I think that there's a certain amount of social respect to people who are going through it. And itching, you kind of sound like a Muppet, right? I do think that itching, it's just a little bit disrespected. You look like a dog with fleas. It's embarrassing to scratch yourself in public. It's inappropriate to scratch yourself in public. I think people just kind of don't take it very seriously.
But I think that there's a certain amount of social respect to people who are going through it. And itching, you kind of sound like a Muppet, right? I do think that itching, it's just a little bit disrespected. You look like a dog with fleas. It's embarrassing to scratch yourself in public. It's inappropriate to scratch yourself in public. I think people just kind of don't take it very seriously.
But I think that there's a certain amount of social respect to people who are going through it. And itching, you kind of sound like a Muppet, right? I do think that itching, it's just a little bit disrespected. You look like a dog with fleas. It's embarrassing to scratch yourself in public. It's inappropriate to scratch yourself in public. I think people just kind of don't take it very seriously.