Apoorva Mandavilli

But if it's not a match, then they have to create a new version of that vaccine and then ramp it up. All of those things take time. And so it would be a while before we were all protected.

But if it's not a match, then they have to create a new version of that vaccine and then ramp it up. All of those things take time. And so it would be a while before we were all protected.

Yeah, that's a really good question. And we actually don't know. So when we have seen this virus in action in Southeast Asia, we've seen mortality rates of something like 50%. But I don't think we can assume that that's going to be the same here because we don't know if, for example, those people died because they were exposed to huge amounts of virus and that's why they got really sick.

Yeah, that's a really good question. And we actually don't know. So when we have seen this virus in action in Southeast Asia, we've seen mortality rates of something like 50%. But I don't think we can assume that that's going to be the same here because we don't know if, for example, those people died because they were exposed to huge amounts of virus and that's why they got really sick.

What we do know is that apart from the one person who died in Louisiana and then the Canadian teenager, most people have had relatively milder symptoms. And I say relatively because some of them did have things like pink eye, but not the pink eye that you and I think of. They had, you know, some level of hemorrhaging blood in the eyes, essentially. Oh my God. Yeah.

What we do know is that apart from the one person who died in Louisiana and then the Canadian teenager, most people have had relatively milder symptoms. And I say relatively because some of them did have things like pink eye, but not the pink eye that you and I think of. They had, you know, some level of hemorrhaging blood in the eyes, essentially. Oh my God. Yeah.

So they did have some severe symptoms, but they did not get sick enough to the point of you know, needing ICU care or dying, except for the two people I mentioned.

So they did have some severe symptoms, but they did not get sick enough to the point of you know, needing ICU care or dying, except for the two people I mentioned.

It wouldn't even need to be anywhere close to 50%. It could be 5% and it would still be more devastating. And it would be really just a very difficult thing to get our arms around. Also, because as you know, for flu tends to affect kids and older people. And in the past pandemics, like the 1918 pandemic, it affected young, healthy people in their 20s and 30s.

It wouldn't even need to be anywhere close to 50%. It could be 5% and it would still be more devastating. And it would be really just a very difficult thing to get our arms around. Also, because as you know, for flu tends to affect kids and older people. And in the past pandemics, like the 1918 pandemic, it affected young, healthy people in their 20s and 30s.

So we don't know exactly what the virus is going to end up doing, but it's not a given that, you know, like COVID, it would be really bad for people who are older or who have certain underlying conditions and that it would mostly leave kids alone. I think we got lucky in those ways with COVID.

So we don't know exactly what the virus is going to end up doing, but it's not a given that, you know, like COVID, it would be really bad for people who are older or who have certain underlying conditions and that it would mostly leave kids alone. I think we got lucky in those ways with COVID.

We don't. I mean, we have some clues just based on what it's been doing as we've been talking about. But one thing that's really clear is that for it to become a pandemic virus, it has to change. And when it changes, we don't know what other ways it's going to change in and whether it'll have to give up some qualities like contagiousness.

We don't. I mean, we have some clues just based on what it's been doing as we've been talking about. But one thing that's really clear is that for it to become a pandemic virus, it has to change. And when it changes, we don't know what other ways it's going to change in and whether it'll have to give up some qualities like contagiousness.

Will it become much milder in its quest to become more contagious? We don't know what trade-offs the virus is going to end up having to make.

Will it become much milder in its quest to become more contagious? We don't know what trade-offs the virus is going to end up having to make.

Yeah, I mean, we do know that over the past year, you know, as little as was going on with things like testing, when there was big news, we did hear from the CDC. You know, they would hold these joint press conferences along with the USDA and the FDA, and they would talk through something like the Nevada case. And they did give out some public health messages.

Yeah, I mean, we do know that over the past year, you know, as little as was going on with things like testing, when there was big news, we did hear from the CDC. You know, they would hold these joint press conferences along with the USDA and the FDA, and they would talk through something like the Nevada case. And they did give out some public health messages.

Like they did say, you know, don't drink raw milk, things like that. They may not have said it loudly or often enough, but they did say it. And I was just getting to a point with them in December where they were starting to say, More things like this is a low risk situation right now, but it could change very quickly. But now they've gone silent.

Like they did say, you know, don't drink raw milk, things like that. They may not have said it loudly or often enough, but they did say it. And I was just getting to a point with them in December where they were starting to say, More things like this is a low risk situation right now, but it could change very quickly. But now they've gone silent.