Derek (More Plates More Dates)

and be hydrated to reflect your actual hematology profile correctly because some people incorrectly think they have a elevated you know hematocrit level when in reality they're just super dehydrated when they go in because they just got up rolled out of bed and are you know dehydrated from hours of sleeping and you know not hydrating properly when they wake up and they just roll in and think that oh I'm gonna have a heart attack and then I gotta donate blood now which might not be the case so I know that's a mouthful but early in the morning

And ideally, you would get a repeat measurement before you make any sort of especially before you make any sort of choices on path forward, because you definitely want to get confirmation if you have a low rating or even one that's like mildly concerning, because, again, these things can be so variable depending on so many factors that you might have.

a blip where it's a snapshot in time of your blood.

You see, you know, a 495 total T and you think, well, that's not great.

It should be closer to a thousand.

That's what I hear is good.

And, you know, all these podcasts and whatnot.

That's what my friends are at.

They're at 900.

Like I only have 495.

I should have way more than that.

And some people haphazardly get on testosterone, shockingly, but it happens.

And there are a lot of clinics that will tell you like, oh yeah, you can get that up.

Let's get this up to, you know, 900.

that's all they need to give you know to justify it to themselves um so yeah you definitely don't want to go off of one reading you want to go off of symptoms and repeat measurement to confirm your findings before you even decide what the path forward is for natural interventions and assessment of what is happening at the organ level and at the hypothalamic pituitary level

Um, in general, I think, um, it does get convoluted because people will see a reference range and assume, and understandably so, like there's a lot of things that people will just say, oh, target the top of the reference range.

This is where you should be.

And in general, it's not a bad recommendation often for things that modulate things.

quality of life related outcomes you know like even when we talk about vitamin D it's like you know you should probably be at like 60 even though the low end is like 30 typically if you were at 40 people would be like you know try and bump that up to 50 or 60 with testosterone people think similarly and justifiably so sometimes but often what is overlooked is the fact that

The actual androgen receptor content, which is like how many androgen receptors you have in like a concentrated area, or also the sensitivity of it, like what kind of transcriptional activity do you get subsequent to binding?