Dr. Aseem Malhotra

So myself and two cardiologists did a systematic review of the totality of drug industry sponsored trials, by the way, and some diet trials, but many drug industry sponsored trials, all of the randomized control trials.

On cholesterol-lowering drugs, statins, PCK9, blah, blah, blah.

Was there a clear relationship as you lowered LDL in low-risk and high-risk patients, Mark?

Okay.

Over 30 studies.

Yeah.

Was there a relationship with lowering LDL and preventing cardiovascular events?

No.

Even in high-risk patients?

Even in high-risk.

It's nonsense.

It's nonsense.

So the question then is... Why do we all so firmly believe that?

So does that mean... But then I said, well, of course, statins have a role.

They do have a benefit from the RCT data, which is small, because I knew already they're anti-inflammatory and anti-clotting.

So it's nothing.

In my view, listen, I could be proven wrong here, but the evidence at the moment looks very clear that there is no consistent relationship, right?

It's definitely not a clear relationship.

So even if it's a weak relationship, Mark,

Let's just argument say, let's say there is a weak benefit in lowering LDL.