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Dr. Bill Harris

👤 Person
447 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

Yeah, in that category, the studies have looked... The ones that have been most effective have used pretty high intakes of EPA and DHA, maybe three to four grams a day, which is the typical American, just for perspective, typical Americans eating that's not taking a fish oil supplement is getting maybe... 0.1 to 0.2 grams a day of EPA DHA, 100 to 200 milligrams a day in their diet.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

Yeah, in that category, the studies have looked... The ones that have been most effective have used pretty high intakes of EPA and DHA, maybe three to four grams a day, which is the typical American, just for perspective, typical Americans eating that's not taking a fish oil supplement is getting maybe... 0.1 to 0.2 grams a day of EPA DHA, 100 to 200 milligrams a day in their diet.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

And we're talking about doses here that I just mentioned for blood pressure in the 1,000 to 2,000 milligram a day, which is a very easy to get dose, but it's a higher dose than maybe just triglyceride lowering might give you, which we might talk about later. It's doable. It's a minor. It's not a major effect on blood pressure. It's a sign that your blood vessels are healthier.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

And we're talking about doses here that I just mentioned for blood pressure in the 1,000 to 2,000 milligram a day, which is a very easy to get dose, but it's a higher dose than maybe just triglyceride lowering might give you, which we might talk about later. It's doable. It's a minor. It's not a major effect on blood pressure. It's a sign that your blood vessels are healthier.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

And we're talking about doses here that I just mentioned for blood pressure in the 1,000 to 2,000 milligram a day, which is a very easy to get dose, but it's a higher dose than maybe just triglyceride lowering might give you, which we might talk about later. It's doable. It's a minor. It's not a major effect on blood pressure. It's a sign that your blood vessels are healthier.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

Your blood vessels are more compliant, more flexible, more able to respond to the heart pushing all that blood out. You don't end up with a high blood pressure. So it's good for blood pressure as well as a variety of other things we'll talk about here.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

Your blood vessels are more compliant, more flexible, more able to respond to the heart pushing all that blood out. You don't end up with a high blood pressure. So it's good for blood pressure as well as a variety of other things we'll talk about here.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

Your blood vessels are more compliant, more flexible, more able to respond to the heart pushing all that blood out. You don't end up with a high blood pressure. So it's good for blood pressure as well as a variety of other things we'll talk about here.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

yeah i mean i think what we hear so much about is inflammation chronic low-grade inflammation from our diet and our lifestyle and pollution in the air um all these things are are pushing this our bodies toward a kind of a chronic inflammatory state now i think the thing that we've seen with omega-3 is that how do they work people say and it's it's

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

yeah i mean i think what we hear so much about is inflammation chronic low-grade inflammation from our diet and our lifestyle and pollution in the air um all these things are are pushing this our bodies toward a kind of a chronic inflammatory state now i think the thing that we've seen with omega-3 is that how do they work people say and it's it's

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

yeah i mean i think what we hear so much about is inflammation chronic low-grade inflammation from our diet and our lifestyle and pollution in the air um all these things are are pushing this our bodies toward a kind of a chronic inflammatory state now i think the thing that we've seen with omega-3 is that how do they work people say and it's it's

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

It's kind of complicated to explain how they work. It's not like a drug that has just one target and bang, you can say this drug fixes that thing. Well, omega-3s are in every cell, every cell membrane. They do good things everywhere. And by about 15 different mechanisms, they do it. But the thing that really counts, it maybe largely comes down to anti-inflammatory.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

It's kind of complicated to explain how they work. It's not like a drug that has just one target and bang, you can say this drug fixes that thing. Well, omega-3s are in every cell, every cell membrane. They do good things everywhere. And by about 15 different mechanisms, they do it. But the thing that really counts, it maybe largely comes down to anti-inflammatory.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

It's kind of complicated to explain how they work. It's not like a drug that has just one target and bang, you can say this drug fixes that thing. Well, omega-3s are in every cell, every cell membrane. They do good things everywhere. And by about 15 different mechanisms, they do it. But the thing that really counts, it maybe largely comes down to anti-inflammatory.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

They put the brakes on, they soften the inflammatory response. And I think that plays out in many, plays out in dementia, plays out in cardiovascular disease, probably plays out in the way the, even the blood is a little bit thinner. when you take more omega-3. So you're less likely to clot in a bad place. That's also part of the good benefits.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

They put the brakes on, they soften the inflammatory response. And I think that plays out in many, plays out in dementia, plays out in cardiovascular disease, probably plays out in the way the, even the blood is a little bit thinner. when you take more omega-3. So you're less likely to clot in a bad place. That's also part of the good benefits.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

They put the brakes on, they soften the inflammatory response. And I think that plays out in many, plays out in dementia, plays out in cardiovascular disease, probably plays out in the way the, even the blood is a little bit thinner. when you take more omega-3. So you're less likely to clot in a bad place. That's also part of the good benefits.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

So inflammation is the one word I would use to describe all the benefits of omega-3. And we saw that in Framingham in our cohort that we looked at, we looked at 10 different blood markers of inflammation. And we correlated those blood markers with the omega-3 level. And for every one of them, higher omega-3, lower inflammatory marker.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

So inflammation is the one word I would use to describe all the benefits of omega-3. And we saw that in Framingham in our cohort that we looked at, we looked at 10 different blood markers of inflammation. And we correlated those blood markers with the omega-3 level. And for every one of them, higher omega-3, lower inflammatory marker.

Dhru Purohit Show
The Mind-Blowing Science of Omega-3 Fatty Acids for Heart Health, Brain Health and Longevity (Rebroadcast)

So inflammation is the one word I would use to describe all the benefits of omega-3. And we saw that in Framingham in our cohort that we looked at, we looked at 10 different blood markers of inflammation. And we correlated those blood markers with the omega-3 level. And for every one of them, higher omega-3, lower inflammatory marker.