Dr. Matthew B. (Matt) (likely the presenter) - Unknown

and so that does lead to weight loss and it reduces waist size body fat percentage and also reduces visceral fat which is the deep fat that surrounds your organs that's secreting pro-inflammatory cytokines and hormones that play a role in type 2 diabetes metabolic syndrome but also you know emerging evidence indicates visceral fat plays a role in cancer as well

Time-restricted eating also lowers blood pressure and improves lipid profiles and improves the HbA1c glucose biomarker.

Early time-restricted eating, so this is typically people that end their last meal about 4 p.m.

Usually early time-restricted eating is about a six-hour window, so it's a shorter eating window.

People that do early time-restricted eating without reducing their calorie intake dramatically improve a variety of metabolic parameters.

Insulin levels are improved, insulin sensitivity is improved, beta cells are more responsive to glucose.

The improvements in blood pressure were so profound that they were equivalent to some antihypertensive treatments.

So that was a big finding of that study.

And then exoxidative stress levels were also improved.

And this is early time-restricted eating.

There's been a meta-analysis of about 12 randomized controlled trials looking at early time-restricted eating.

Again, this was defined at stopping your last meal at about 4 PM.

And then comparing it to later time-restricted eating, so people that were stopping their meals not at four, but a little bit later.

And all the eating windows were either four to 10 hours.

And early time-restricted eating does have more profound effects on glucose regulation.

Largely because, again, we're more insulin sensitive earlier, less insulin sensitive later.

Once the melatonin starts to kick in, again, it gets much worse.

So early time-restricted eating can improve fasting blood glucose levels and insulin resistance more than later time-restricted eating.

but it also has a more profound effect on the blood pressure regulation, so lowering blood pressure.

Late time restricted eating can sort of maintain blood pressure, but it doesn't improve it like the early time restricted eating.