Dr. Nathan Bryan

That's very interesting.

That's what nitric oxide does.

Well, I mean, there's risk factors.

So everything that we know, risk factors that are associated or lead to a loss of nitric oxide production increase your risk for developing dementia and Alzheimer's.

So what is that?

High blood pressure, erectile dysfunction, smoking, poor diet, sedentary lifestyle, all those decrease nitric oxide production.

The end result is lack of blood flow, insulin resistance, and then eventually Alzheimer's.

Yeah, so erectile dysfunction precedes dementia and Alzheimer's.

Oh, it does?

So it's like a... Yeah, it's what we call the canary in the coal mine, because think about it.

Erectile dysfunction is the lack of the ability to dilate the blood vessels of the sex organs.

So when we need to recall memory or have some executive function, we've got to dilate, we've got to perfuse certain regions of the brain.

So if you can't dilate the blood vessels of the sex organs when you're going to have sex, then you can't, that same dysfunction occurs in the brain, in the cerebral organs.

Wow.

So now you've lost the ability to dilate blood vessels, increase blood flow on demand.

And that's what nitric oxide does.

So ED is a risk factor for heart disease, Alzheimer's, diabetes.

And it's all related to lack of nitric oxide.

No, look, and here's the therapeutic solution is drugs like Viagra and Cialis, the PD5 inhibitors.

But we know that those drugs only work in 50% of the men in which they're prescribed.