Dr. Shebani Sethi
speaker
159 appearances
2 recordings
1 series
first heard Feb 2025
last heard Mar 2025
Dr. Shebani Sethi’s voice in public audio — every appearance, attributed to the second.
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Coming up on this episode of The Dr. Hyman Show.
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Right now, Bioptimizers is offering my listeners a special discount. Just go to bioptimizers.com slash hymen and use code HYMEN10 at checkout. Don't wait. Your body will thank you. Before we jump into today's episode, I'd like to note that while I wish I could help everyone via my personal practice, there is simply not enough time for me to do this at scale.
That's why I've been busy building several passion projects to help you. If you're looking for data about your biology, check out Function Health for real-time lab insights. And if you're in need of deepening your knowledge around your health journey, check out my membership community, the Hyman Hive.
And if you're looking for curated and trusted supplements and health products for your health journey, visit my website at drhyman.com for a summary of my favorite and thoroughly tested products. We have a mental health crisis. Globally, 300 million people are suffering from anxiety. 280 million people are suffering from depression.
Now, from treating thousands of patients over the last 30 years, I've learned that depression is mostly not in your head. It's in your body. When I treat patients' gut issues, and this is something I just discovered almost by accident, their mental health would magically get better. But it wasn't magic. It was science. I just didn't understand at the time. It's not magic.
Gut dysfunction is not the only cause of our mental health crisis. There's a lot of things that are driving it, but it's a major factor that's often unaddressed. Now, when your gut is unhealthy, when it's inflamed, your brain is unhealthy and also inflamed. When we fix... the gut, then brain health, mood, memory, focus, and mental health all improve. Now, why is this important?
Inflammation is a huge driver of most of our mental health issues from depression, anxiety, autism, ADD, even things like Alzheimer's, schizophrenia, bipolar disease, all linked to inflammation of the brain. And where is this inflammation coming from? Obviously our diet, but also from our microbiome. And I learned this early in my medical practice.
In fact, on one of my early books called The Ultra Mind Solution, a deep dive into the way the body affects the brain, including the gut and the microbiome. Now, conventional medicine views these two things as completely separate and unrelated. And typically, if you have GI symptoms, you go to the GI doctor, a gastroenterologist. And if you have mental health issues, you go to a psychiatrist.
to help with balancing your mood. They prescribe different drugs for each condition instead of understanding the root cause and treating that. And then we're gonna talk about how this works, why it's important, what the science is, and some of my clinical case studies, which are quite compelling.
Now in functional medicine, we know the gut and the brain are intimately connected and that the health of one directly impacts the other. So you can't fix the brain without fixing the gut and you can't fix the gut without fixing the brain. So it's bi-directional. It's not mind, body, body, mind, body, mind, mind, body. It's both, right? When we do that,
And I've done this in thousands of patients, and the studies back this up, and more and more data's coming out. Guys like Chris Palmer, Uma Naidoo, a psychiatrist from Stanford, and integrated psychiatrists, functional psychiatrists are all seeing this, and data is really exploding on this. When I wrote the book 15 years ago, there was data, but it was limited.
But I saw it, and I saw the kind of whispers in the wind let's say, the sort of tea leaves. And I was like, okay, this is really something. And when I started to do this with my patients and when we do this now, we see profound improvements in mood and obviously digestive health and all other areas of health. So gut is just linked to everything.
So fix the gut, fix the body, fix the gut, fix the brain. I know how powerful this is and how powerful functional medicine is for fixing depression because I also had it. myself. And it wasn't because of something that had to do with my psycho-emotional health, but my physical health. My brain literally broke one day in 1996. I felt like I had ADD, depression, and dementia all at once.
I saw lots of doctors, psychiatrists. No one could find the cause, although they wanted me to take Prozac for my symptoms. And no one could agree on the diagnosis. Some said I had depression. Others said I had chronic fatigue. And in fact, I did have chronic fatigue. And I started to de- dive into the literature.
And I consulted with other doctors and scientists, people on the leading edge of medicine. And I started to do some experimentation. And when I came to understand that it wasn't just one thing that caused my brain to break, it was accumulation of a lot of things. Diet stuff, stress, environmental toxins like mercury was a big factor. My gut was just a mess. In fact, that's what happened.
I had mercury underlying all this. And then one day I got some kind of gut infection up in Maine at a camp. And then boom, my gut was off. And it didn't get back on track for many years until I figured out how to fix it. And all that leads to inflammation. So rebalancing my gut microbiome, getting rid of the mercury. It was messing up my gut because mercury interferes with gut function.
It was the key to getting my brain and health back. I also saw this with so many of my patients. I had a woman who had severe OCD. She wouldn't clean up her house for years because she didn't want to move things around on the floor. Looked at her health and her biology and try to see what was going on. And in functional medicine, we just take out the bad stuff, put in the good stuff.
So I saw she had a lot of bad bugs in her gut, a lot of overgrowth of yeast, and I gave her basically an antibiotic and a fungal that was designed to kill those particular bugs. And literally overnight, her OCD went away and she was able to clean up her whole house after decades. I also had a little girl who was a sweet little girl, nine years old, but was a terror.
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