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Jonathan Lambert

👤 Person
645 total appearances

Appearances Over Time

Podcast Appearances

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, again, it's exploratory, but just kind of blew my mind. So we were doing another test with these, we call them upper trained or positive anticipation trained rats, where they were in an arena. And A student said, Dr. Lambert, why does the rat have its tail sticking straight up? And it was like an umbrella, you know, kind of a hook.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, again, it's exploratory, but just kind of blew my mind. So we were doing another test with these, we call them upper trained or positive anticipation trained rats, where they were in an arena. And A student said, Dr. Lambert, why does the rat have its tail sticking straight up? And it was like an umbrella, you know, kind of a hook.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, again, it's exploratory, but just kind of blew my mind. So we were doing another test with these, we call them upper trained or positive anticipation trained rats, where they were in an arena. And A student said, Dr. Lambert, why does the rat have its tail sticking straight up? And it was like an umbrella, you know, kind of a hook.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And sure enough, the upper trained or anticipatory trained animals had it sticking up more. And I didn't know what this meant. So I put a picture on social media. I said, has anyone seen this? Because I just hadn't. And a few people said, oh, yes, if you inject morphine into a mouse or a rodent, their tail goes up.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And sure enough, the upper trained or anticipatory trained animals had it sticking up more. And I didn't know what this meant. So I put a picture on social media. I said, has anyone seen this? Because I just hadn't. And a few people said, oh, yes, if you inject morphine into a mouse or a rodent, their tail goes up.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And sure enough, the upper trained or anticipatory trained animals had it sticking up more. And I didn't know what this meant. So I put a picture on social media. I said, has anyone seen this? Because I just hadn't. And a few people said, oh, yes, if you inject morphine into a mouse or a rodent, their tail goes up.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And I thought, have we changed these opiates in these animals through behavioral training? So dopamine for pleasure and opiates for well-being, that's a pretty good cocktail from behavioral training. And I've introduced this word behaviorceuticals that we can change our— So it was maybe the perfect behaviorceutical, but we're still exploring.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And I thought, have we changed these opiates in these animals through behavioral training? So dopamine for pleasure and opiates for well-being, that's a pretty good cocktail from behavioral training. And I've introduced this word behaviorceuticals that we can change our— So it was maybe the perfect behaviorceutical, but we're still exploring.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

And I thought, have we changed these opiates in these animals through behavioral training? So dopamine for pleasure and opiates for well-being, that's a pretty good cocktail from behavioral training. And I've introduced this word behaviorceuticals that we can change our— So it was maybe the perfect behaviorceutical, but we're still exploring.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

It's just great to watch the animals and they give you clues about what to look at next.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

It's just great to watch the animals and they give you clues about what to look at next.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

It's just great to watch the animals and they give you clues about what to look at next.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, so we found that just going through the training itself, regardless if they learn to drive or not, that changed at least the hormone profiles. Oh, so it doesn't even matter if they're a good driver or not. They just like driving. It's the process. You're journey, not the destination. Yeah. Really.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, so we found that just going through the training itself, regardless if they learn to drive or not, that changed at least the hormone profiles. Oh, so it doesn't even matter if they're a good driver or not. They just like driving. It's the process. You're journey, not the destination. Yeah. Really.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

Yeah, so we found that just going through the training itself, regardless if they learn to drive or not, that changed at least the hormone profiles. Oh, so it doesn't even matter if they're a good driver or not. They just like driving. It's the process. You're journey, not the destination. Yeah. Really.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

there's research to suggest that stress can impair neuroplasticity or at least the healthier kind of versions of plasticity. So if this training is helping them regulate their emotions and have lower levels of stress hormones, that's going to have probably a positive impact on the brain. So if we know more about how we can intentionally and systematically change our behavior,

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

there's research to suggest that stress can impair neuroplasticity or at least the healthier kind of versions of plasticity. So if this training is helping them regulate their emotions and have lower levels of stress hormones, that's going to have probably a positive impact on the brain. So if we know more about how we can intentionally and systematically change our behavior,

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

there's research to suggest that stress can impair neuroplasticity or at least the healthier kind of versions of plasticity. So if this training is helping them regulate their emotions and have lower levels of stress hormones, that's going to have probably a positive impact on the brain. So if we know more about how we can intentionally and systematically change our behavior,

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

to change our brains in healthy ways. Most of the research is related to changing neurochemistry through pharmaceuticals, but I wanted there to be more attention on the behavior. We know that cognitive behavioral therapy is very effective with humans, but we don't have good preclinical models. We're not sure exactly what that's doing.

Short Wave
These Rats Can Drive. What's Happening In Their Brains?

to change our brains in healthy ways. Most of the research is related to changing neurochemistry through pharmaceuticals, but I wanted there to be more attention on the behavior. We know that cognitive behavioral therapy is very effective with humans, but we don't have good preclinical models. We're not sure exactly what that's doing.