Louisa Nicola
👤 PersonAppearances Over Time
Podcast Appearances
But we also know that it can help with cell membrane fluidity, the way that your cells are moving throughout your body and in your brain. So it does so much. I could list about a thousand things that the omega-3 fatty acid pill does.
But we also know that it can help with cell membrane fluidity, the way that your cells are moving throughout your body and in your brain. So it does so much. I could list about a thousand things that the omega-3 fatty acid pill does.
But we also know that it can help with cell membrane fluidity, the way that your cells are moving throughout your body and in your brain. So it does so much. I could list about a thousand things that the omega-3 fatty acid pill does.
Yeah.
Yeah.
Yeah.
It is neuroprotective.
It is neuroprotective.
It is neuroprotective.
I want to first clarify, I think this is really important to understand the difference between genetic mutations and genetic risk factors. So when we have genetic mutations, let's just say we've got around 25,000 genes in the human genome, If we have a miscalculation on one of those genes, you will have a certain disease. If you've got a mutation on chromosome 4, you'll get Huntington's disease.
I want to first clarify, I think this is really important to understand the difference between genetic mutations and genetic risk factors. So when we have genetic mutations, let's just say we've got around 25,000 genes in the human genome, If we have a miscalculation on one of those genes, you will have a certain disease. If you've got a mutation on chromosome 4, you'll get Huntington's disease.
I want to first clarify, I think this is really important to understand the difference between genetic mutations and genetic risk factors. So when we have genetic mutations, let's just say we've got around 25,000 genes in the human genome, If we have a miscalculation on one of those genes, you will have a certain disease. If you've got a mutation on chromosome 4, you'll get Huntington's disease.
A genetic mutation in the dementia space involves three genes. You've got presenilin 1, presenilin 2, and the APP gene. right? They are mutations. So if you have these three genes, we know that you are going to get some form of dementia. The other risk factor genes, which I know that you know what they are, we've got two of them called ApoE4.
A genetic mutation in the dementia space involves three genes. You've got presenilin 1, presenilin 2, and the APP gene. right? They are mutations. So if you have these three genes, we know that you are going to get some form of dementia. The other risk factor genes, which I know that you know what they are, we've got two of them called ApoE4.
A genetic mutation in the dementia space involves three genes. You've got presenilin 1, presenilin 2, and the APP gene. right? They are mutations. So if you have these three genes, we know that you are going to get some form of dementia. The other risk factor genes, which I know that you know what they are, we've got two of them called ApoE4.
If you have the ApoE4 allele, you get one from mom, one from dad, it raises your risk of getting the disease. So they are risk genes. So I think it's really important to differentiate between the two. So what's happening now is that out of that 55 million people that have the genetic risk factors for Alzheimer's disease, Only 3% to 5% have the APOE4 gene. either one or two.
If you have the ApoE4 allele, you get one from mom, one from dad, it raises your risk of getting the disease. So they are risk genes. So I think it's really important to differentiate between the two. So what's happening now is that out of that 55 million people that have the genetic risk factors for Alzheimer's disease, Only 3% to 5% have the APOE4 gene. either one or two.
If you have the ApoE4 allele, you get one from mom, one from dad, it raises your risk of getting the disease. So they are risk genes. So I think it's really important to differentiate between the two. So what's happening now is that out of that 55 million people that have the genetic risk factors for Alzheimer's disease, Only 3% to 5% have the APOE4 gene. either one or two.
So they have a higher risk of getting the disease. But the other 95% are getting diagnosed with Alzheimer's disease without having the mutations or the risk genes. So that begs the question of why. You could live your entire life and not get Alzheimer's. Correct. Even, you know, regardless of genes, by the way, regardless of not having the genes. I truly believe that.
So they have a higher risk of getting the disease. But the other 95% are getting diagnosed with Alzheimer's disease without having the mutations or the risk genes. So that begs the question of why. You could live your entire life and not get Alzheimer's. Correct. Even, you know, regardless of genes, by the way, regardless of not having the genes. I truly believe that.