Nick Norwitz

You can get a statistically significant result in a trial that you publish in the New England Journal, and it can still help only a minority of people.

You can get a statistically significant result in a trial that you publish in the New England Journal, and it can still help only a minority of people.

I think the top 10 drugs only help like 1 to 4 to 1 in 10 people who take them.

I think the top 10 drugs only help like 1 to 4 to 1 in 10 people who take them.

I think the top 10 drugs only help like 1 to 4 to 1 in 10 people who take them.

I think the first thing to acknowledge is there's not a good definition of metabolic health. When we're talking about scientific communication, there are some terms that have very strict definitions and criteria and other terms that are more like Porn, where you know it when you see it. Another example would be ultra-processed foods.

I think the first thing to acknowledge is there's not a good definition of metabolic health. When we're talking about scientific communication, there are some terms that have very strict definitions and criteria and other terms that are more like Porn, where you know it when you see it. Another example would be ultra-processed foods.

I think the first thing to acknowledge is there's not a good definition of metabolic health. When we're talking about scientific communication, there are some terms that have very strict definitions and criteria and other terms that are more like Porn, where you know it when you see it. Another example would be ultra-processed foods.

Really defining that scientifically is difficult, but it's a useful term and heuristic in the public sphere. So I'll just say up front, I feel like metabolic health is similar where it encompasses a lot of things and there's a lot of definitions, but I just want to be up front. There is no consensus on what the definition is. With that said, there are different ways to slice it.

Really defining that scientifically is difficult, but it's a useful term and heuristic in the public sphere. So I'll just say up front, I feel like metabolic health is similar where it encompasses a lot of things and there's a lot of definitions, but I just want to be up front. There is no consensus on what the definition is. With that said, there are different ways to slice it.

Really defining that scientifically is difficult, but it's a useful term and heuristic in the public sphere. So I'll just say up front, I feel like metabolic health is similar where it encompasses a lot of things and there's a lot of definitions, but I just want to be up front. There is no consensus on what the definition is. With that said, there are different ways to slice it.

The way I like to think about it is it's when your body's systems are running in a way to optimize performance and minimize risk of chronic disease. You can start to intuit that through certain biomarkers. So there's like canaries in the coal mine for poor metabolic health. Like if you have high fasting insulin or insulin resistance score,

The way I like to think about it is it's when your body's systems are running in a way to optimize performance and minimize risk of chronic disease. You can start to intuit that through certain biomarkers. So there's like canaries in the coal mine for poor metabolic health. Like if you have high fasting insulin or insulin resistance score,

The way I like to think about it is it's when your body's systems are running in a way to optimize performance and minimize risk of chronic disease. You can start to intuit that through certain biomarkers. So there's like canaries in the coal mine for poor metabolic health. Like if you have high fasting insulin or insulin resistance score,

Things like triglyceride to HDL ratio or, you know, features of metabolic syndrome. You look at your waist circumference, your visceral fat. There's a lot of things you can look at.

Things like triglyceride to HDL ratio or, you know, features of metabolic syndrome. You look at your waist circumference, your visceral fat. There's a lot of things you can look at.

Things like triglyceride to HDL ratio or, you know, features of metabolic syndrome. You look at your waist circumference, your visceral fat. There's a lot of things you can look at.

I think a way to think about it is, I don't know if I came up with this analogy, I can't imagine I did, but that of the tree of metabolic illness, where, you know, if you look at a tree and you look at all the different branches, you can see each different branch of the disease, obesity, diabetes, cardiovascular disease.

I think a way to think about it is, I don't know if I came up with this analogy, I can't imagine I did, but that of the tree of metabolic illness, where, you know, if you look at a tree and you look at all the different branches, you can see each different branch of the disease, obesity, diabetes, cardiovascular disease.

I think a way to think about it is, I don't know if I came up with this analogy, I can't imagine I did, but that of the tree of metabolic illness, where, you know, if you look at a tree and you look at all the different branches, you can see each different branch of the disease, obesity, diabetes, cardiovascular disease.