Sean Gibbons

So we know it does affect things, but I think more work needs to be done to understand it better.

So we know it does affect things, but I think more work needs to be done to understand it better.

So in this population of people we were studying, we had questionnaire data about their lifestyle. We found some perhaps unsurprising things. So for example, those people who were in this Goldilocks zone of pooping, they tended to eat more vegetables and fruits. So eat your fresh fruits and vegetables. They also tended to be more hydrated. So be sure to drink plenty of water.

So in this population of people we were studying, we had questionnaire data about their lifestyle. We found some perhaps unsurprising things. So for example, those people who were in this Goldilocks zone of pooping, they tended to eat more vegetables and fruits. So eat your fresh fruits and vegetables. They also tended to be more hydrated. So be sure to drink plenty of water.

That helps with motility. And they had higher levels of activity. They were wearing Fitbit trackers. So we could track how many steps they were taking. So between diet, exercise and hydration, these simple factors can help improve your bowel health.

That helps with motility. And they had higher levels of activity. They were wearing Fitbit trackers. So we could track how many steps they were taking. So between diet, exercise and hydration, these simple factors can help improve your bowel health.

Well, if you're experiencing chronic bouts of constipation or diarrhea, you should talk to your clinician because these could be underlying conditions of other problems in your body. But bowel movement frequency itself isn't often monitored that closely by clinicians. However, our study, I think, points to the fact that maybe that's the future, right?

Well, if you're experiencing chronic bouts of constipation or diarrhea, you should talk to your clinician because these could be underlying conditions of other problems in your body. But bowel movement frequency itself isn't often monitored that closely by clinicians. However, our study, I think, points to the fact that maybe that's the future, right?

Maybe the future of medicine should include this as a parameter that we pay closer attention to. Because even though we haven't causally proven that the rise of these metabolites in the blood due to constipation will eventually lead to something like a neurodegenerative disease, it seems likely that that could be the case.

Maybe the future of medicine should include this as a parameter that we pay closer attention to. Because even though we haven't causally proven that the rise of these metabolites in the blood due to constipation will eventually lead to something like a neurodegenerative disease, it seems likely that that could be the case.

And that by having long-term levels of constipation or diarrhea, we might be increasing our risk for chronic diseases. So it might be very important to pay attention to it and to keep in that Goldilocks zone.

And that by having long-term levels of constipation or diarrhea, we might be increasing our risk for chronic diseases. So it might be very important to pay attention to it and to keep in that Goldilocks zone.

I don't have a strong take on it. Again, I'm not a clinician. I'm a PhD, so I can't give medical advice. I don't have a lot of data on colonics, so I don't know a ton there, other than it is the case that people who are getting a colonoscopy get the functional equivalent of a colonic right there. They get cleaned out before the procedure.

I don't have a strong take on it. Again, I'm not a clinician. I'm a PhD, so I can't give medical advice. I don't have a lot of data on colonics, so I don't know a ton there, other than it is the case that people who are getting a colonoscopy get the functional equivalent of a colonic right there. They get cleaned out before the procedure.

What we find is in people who take Miralax or have themselves cleaned out, It's a window of opportunity for opportunistic pathogens. So we'll sometimes see that people are colonized by organisms like Clostridioides difficile. Even if they don't get sick, they're sort of benignly colonized by these things in these windows of opportunity when their commensal microbiome biomass is depleted.

What we find is in people who take Miralax or have themselves cleaned out, It's a window of opportunity for opportunistic pathogens. So we'll sometimes see that people are colonized by organisms like Clostridioides difficile. Even if they don't get sick, they're sort of benignly colonized by these things in these windows of opportunity when their commensal microbiome biomass is depleted.

And then it can lay in wait to a future date when maybe you take antibiotics and your microbes are again disrupted and this pathogen can look around and say, oh, now there's an opportunity to cause disease. But long story short, I think colonics, I don't know exactly what the health implications are other than they might be windows of opportunity for these pathogens to invade.

And then it can lay in wait to a future date when maybe you take antibiotics and your microbes are again disrupted and this pathogen can look around and say, oh, now there's an opportunity to cause disease. But long story short, I think colonics, I don't know exactly what the health implications are other than they might be windows of opportunity for these pathogens to invade.

I guess I want people to think about their microbes. The microbiome, it's a fairly emergent field. It's about 20 years old now. We're just beginning to understand how to manipulate our microbiota to optimize our health. While the microbiome doesn't have a super, super strong effect on human health and disease in the short term, it seems to be critical for our long-term health and longevity.

I guess I want people to think about their microbes. The microbiome, it's a fairly emergent field. It's about 20 years old now. We're just beginning to understand how to manipulate our microbiota to optimize our health. While the microbiome doesn't have a super, super strong effect on human health and disease in the short term, it seems to be critical for our long-term health and longevity.