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Wendy Zuckerman

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
2083 total appearances

Appearances Over Time

Podcast Appearances

Science Vs
Peptides: The Ultimate Body Hack?

So when you look at our entire DNA, you roll it out like toilet paper.

Science Vs
Peptides: The Ultimate Body Hack?

Those 20,000 genes are a tiny fraction of the role.

Science Vs
Peptides: The Ultimate Body Hack?

For years, that so-called junk DNA, and more generally, the parts of our DNA that didn't code for proteins, it was like a cipher that many scientists, including Hassi, were trying to decode.

Science Vs
Peptides: The Ultimate Body Hack?

And over the years, they worked out that these mysterious chunks of DNA do loads of important stuff.

Science Vs
Peptides: The Ultimate Body Hack?

Including, get this, coding for not big, complicated proteins, but little baby proteins.

Science Vs
Peptides: The Ultimate Body Hack?

Peptides.

Science Vs
Peptides: The Ultimate Body Hack?

But fast forward to today, and Hassi's team has found a bunch of peptides hanging out in weird parts of our DNA.

Science Vs
Peptides: The Ultimate Body Hack?

His lab likes to give them Yiddish names.

Science Vs
Peptides: The Ultimate Body Hack?

Please tell me there's one called chutzpah.

Science Vs
Peptides: The Ultimate Body Hack?

Mensch.

Science Vs
Peptides: The Ultimate Body Hack?

Hasse's lab has found these peptides in what's called our mitochondrial DNA.

Science Vs
Peptides: The Ultimate Body Hack?

Mitochondria are known as the powerhouses of our cells.

Science Vs
Peptides: The Ultimate Body Hack?

They kind of look like carpet beetle larvae, but what they do is pump out fuel for our body to use for energy.

Science Vs
Peptides: The Ultimate Body Hack?

And in humans, different versions of Hasse's mitochondrial peptides have been linked to lowering our risk of various diseases.

Science Vs
Peptides: The Ultimate Body Hack?

In lab and animal studies, these peptides can affect muscle growth, metabolism, oxidative stress, insulin sensitivity and cognition.

Science Vs
Peptides: The Ultimate Body Hack?

And we just keep finding more peptides.

Science Vs
Peptides: The Ultimate Body Hack?

A study published in May this year found more than 3,000 peptides hiding in the mysterious chunks of our DNA.

Science Vs
Peptides: The Ultimate Body Hack?

And we're not sure what many of them even do.

Science Vs
Peptides: The Ultimate Body Hack?

Hussey is excited that there is this whole world of tiny proteins, actors in the human body that we didn't even know existed.

Science Vs
Peptides: The Ultimate Body Hack?

And he reckons it could change the way that we understand some diseases, possibly opening the door to different kinds of medicine.