As part of the TMM4950 Sci-Comm special episode, J.P. Doyle from the University of Ottawa interviews Dr. Alexandre Stewart, a distinguished scientist from the University of Ottawa Heart Institute and a director of the Laboratory of Translational Genomics. In this episode, Dr. Stewart and J.P. discuss the viral origins of breast cancer, specifically the hypothesis that the Mouse Mammary Tumor Virus (MMTV) may cause breast cancer in humans. They explored the "second hit" hypothesis, geographic variations in cancer incidence between Western and Eastern Europe, and the potential for future vaccines and anti-retroviral therapies to prevent and treat the disease.Learn more about Dr. Stewart: https://www.ottawaheart.ca/profile/stewart-alexandreRead more about the paper: https://doi.org/10.3390/v140305590:10 - Introduction to Dr. Alexandre Stewart and Breast Cancer1:04 - Inspiration: The Biology of Breast Cancer and Immunosuppression2:48 - Geographic Variation and the Migrant Effect4:25 - Mechanisms: How MMTV and Human Papillomavirus (HPV) differ in causing cancer7:05 - The Senegal Study: Globalization and Mouse Populations10:22 - Vaccines and Anti-Retroviral Parallels14:34 - ConclusionMusic Credit: This podcast episode features the song 'Documentary' by SigmaMusicArt (Mikhail Smusev) via Pixabay, available under the Pixabay Content License. Listen more:https://pixabay.com/music/modern-classical-documentary-264400/J.P. Doyle (Host, Content Writer), Barry Ngo (Producer, Editor, Promoter)

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