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Curing with Sound

Ep-23: Treating Melanoma with Focused Ultrasound and Immunotherapy: A Conversation with Lynn Dengel, MD

04 Feb 2025

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In this episode of Curing with Sound, Lynn Dengel, MD, a surgical oncologist at UVA Health, discusses her groundbreaking clinical trial combining focused ultrasound with immunotherapy to treat patients with advanced melanoma.  She shares insights into how this Foundation-funded trial – which is still enrolling patients – could help those who don't benefit from standard immunotherapy alone. Key points from the conversation: Melanoma is the most invasive type of skin cancer and accounts for the majority of skin cancer deaths. More than 100,000 Americans are diagnosed with melanoma each year. The study will enroll approximately 11 participants with advanced melanoma who are receiving a cancer immunotherapy drug (PD-1 antibody blockade) as part of their regular care and having the melanoma surgically removed. Dr. Dengel explains how focused ultrasound not only targets tumor tissue but may also create an enhanced environment for immunotherapy to work more effectively. As a senior advisor to the Foundation's immunotherapy program, Dr. Dengel highlights the value of cross-institutional collaboration in advancing focused ultrasound research and improving patient outcomes. UVA Health Study: Seeking Adult Patients with Advanced Melanoma Who are Receiving Immune Therapy and Who are Planning to Receive Surgery - MORE INFO EPISODE TRANSCRIPT ---------------------------- QUESTIONS? Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.  Email [email protected] if you have questions about focused ultrasound or the Foundation.  FUSF SOCIAL MEDIA LinkedIn X Facebook Instagram TikTok YouTube FUSF WEBSITE https://www.fusfoundation.org SIGN UP FOR OUR FREE NEWSLETTER https://www.fusfoundation.org/newsletter-signup/ READ THE LATEST NEWSLETTER https://www.fusfoundation.org/the-foundation/news-media/newsletter/ DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK) https://www.fusfoundation.org/read-the-tumor-by-john-grisham/

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