Episode 3: Real-World Clinical DDI Cases | Juan Ambrosioni & José Moltó

In the third podcast, Dr. Burger discusses the added value of reporting outcomes of real-world cases in patients with HIV caused by drug-drug interactions (DDIs) with Dr. Ambrosioni and Dr. Molto.Several databases are available for DDI management, with discrepancies often occurring between the databases. The differences may be caused by extrapolations from studied interactions to predict the DDI potential for unknown drug combinations. The relevance of the unstudied DDIs is often unknown.Reporting the outcomes of real-world cases can determine the relevance of DDIs. The article discusses real-world cases between antiretrovirals (ARVs) and comedications reported on www.clinicalcasesDDIs.com. Twenty percent of the reported cases involve over-the-counter drugs, which are often not recorded in patient files.The following topics will be discussed during the podcast: - the challenges of DDI management of ARVs with comedications; - the added value of reporting outcomes of real-world cases; and- the underestimated risks of over-the-counter (OTC) drug use. Listen to the podcast for all the tips and take-home messages!Read the full article here: https://link.springer.com/article/10.1007/s40121-024-00935-0

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