Episode 7: Pharmacokinetics and Green Tea: The Catechin Connection

In the seventh episode, Prof. Dr. David Burger discusses with Nicki Kyriacou the review article: “Green tea catechins as perpetrators of drug pharmacokinetic interactions”. You might think: “Green tea?– I drink it all the time! “But is it really that innocent?Tune in now as we explore how catechins-compounds found in green tea, like (-)-epigallocatechin-3-gallate – can impact drug pharmacokinetics. These compounds can alter drug solubility, transporter activity, and metabolism, potentially affecting the concentration of therapeutic drugs such as atorvastatin, digoxin, and sildenafil.The following key topics will be discussed in the podcast:The scope and intensity of green tea interaction studies;Different green tea formulations and their impact on drug interactions;Relevance for specific patient populations (especially cardiovascular medications);Why green tea reduces most drug concentrations – but increases sildenafil levels;The role of timing in green tea consumption vs. co-medication; andPractical guidance for clinicians and pharmacists to assess potential interaction.Don’t miss this insightful discussion on the drug interaction potential of green tea and the practical takeaways for health professionals!

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