Episode 281 - The Future of Closed Loop Diabetes Therapy - Xeris Biopharma and Beta Bionics announce partnership to produce bi-hormonal insulin pump with Paul Edick and Sean Saint

In this episode of Diabetics doing things, Rob interviews Paul Edick from Xeris Biopharma and Sean Saint from Beta Bionics. They discuss the formal partnership announcement between Xeris Biopharma and Beta Bionics, focusing on the development of a bi-hormonal insulin pump for diabetes management. The conversation touches on the challenges and benefits of the partnership, the development process, and the potential impact on diabetes care. Topics discussed: 1. Partnership between Xeris Biopharma and Beta Bionics 2. The unique challenges faced by a bihormonal pump compared to traditional insulin pumps. 3. The formulation process of the pump and collaboration between Xeris and Beta Bionics. 4. The upcoming phase 2 and phase 3 clinical trials. 5. The importance of glucagon in diabetes management and the need for increased awareness and availability of glucagon. 6. The potential for a fully automated diabetes therapy experience. 7. The role of technology in reducing the burden of diabetes management and enhancing quality of life. 8. The journey towards regulatory approval and commercialization. 9. The historical context of glucagon use and the evolving perceptions around its importance. 10. The positive impact of the partnership on advancing diabetes care and glycemic control. Key takeaways: * The partnership between Xeris Biopharma and Beta Bionics aims to develop a bihormonal pump for diabetes management. * The collaboration involves overcoming unique challenges associated with incorporating both insulin and glucagon in the pump. * The development process includes formulation, clinical trials, and regulatory approval. * The partnership highlights the importance of increasing awareness and availability of glucagon for diabetes patients. * The ultimate goal is to provide a hands-off, automated diabetes therapy experience to improve quality of life for individuals with diabetes. References: * Xeris Biopharma * Beta Bionics 00:00  Exploring Inspiring Stories of People with Diabetes and Industry Announcements 00:18  Exciting Partnership Announcement: Xeris Biopharma and Beta Bionics Join Forces for Innovative Diabetes Solution 03:58  Revolutionizing Diabetes Care with Biohormonal Pump and Xerasol Technology 08:52  Exploring the Future of Glucagon Use and Reducing Stigma in Diabetes Management 13:41  Revolutionizing Diabetes Therapy: The Future of Automated Insulin and Glucagon Pump Systems 23:41  Overcoming Fear and Stigma: The Journey with Glucagon and the Future of Insulin Pumps 25:17  Challenges and Partnerships in Developing a Bi-Hormonal Pump for Diabetes Management 30:47  Exciting Innovations in Diabetes Care: A Look into Bi Hormonal Pumps

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