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Dr. Joseph Mercola - Take Control of Your Health

Adrenal Shutdown: The Silent Crisis Behind Long-Term Steroid Use - AI Podcast

14 Jun 2025

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Story at-a-glance Corticosteroids shut down natural cortisol production; even short-term use as brief as 14 days suppresses adrenal function, creating dangerous dependency on synthetic hormones A European study reveals widespread risk; over 500,000 patients showed six times higher adrenal insufficiency rates with oral steroids; even "safe" inhaled versions increased risk by 55% Sudden steroid withdrawal triggers emergency situations requiring immediate medical care due to collapsed fluid and electrolyte balance Nearly half (48.7%) of oral steroid patients develop adrenal suppression, yet most aren't warned about or tested for this serious condition Recovery requires metabolic repair; focus on reducing inflammation, fixing insulin resistance, optimizing sleep cycles and supporting natural cortisol rhythms rather than more medications

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