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Dr. Joseph Mercola - Take Control of Your Health

Beyond Bioavailability — What Research Shows About Flavanols' Effectiveness

22 Dec 2025

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Flavanols are plant compounds in cocoa, berries, and tea with low bioavailability, meaning only a small portion enters the bloodstream A new animal study found that oral flavanol doses of 25 to 50 milligrams per kilogram (mg/kg) activated the subjects' brains within minutes Flavanols are a type of flavonoid within the polyphenol family. This hierarchy clarifies their differences and explains why foods have unique combinations that offer specific health benefits If you choose cocoa flavanol supplements, don't fall for flashy marketing; whenever possible, stick to a nutritious food-first approach Along with consuming flavanol-rich foods, pairing them with regular physical activity and a nutrient-dense, plant-focused diet helps support long-term brain health and cardiovascular resilience

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