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Dr. Joseph Mercola - Take Control of Your Health

Depression's Physical Toll: How it Impacts Chronic Disease

01 Apr 2025

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Story at-a-glance Aside from being a mental health issue, depression also speeds up the onset of chronic illnesses like diabetes, heart disease and arthritis, making them appear years earlier than expected People with depression are significantly more likely to be hospitalized for serious physical conditions, with some illnesses requiring up to five times more hospital visits compared to those without depression Depression causes chronic stress and inflammation, which damage your body at a cellular level, weakening your immune system, increasing blood sugar issues and accelerating disease progression Poor sleep and gut health disruptions in depressed people worsen both mental and physical health, leading to higher rates of infections, digestive problems and metabolic disorders Breaking the cycle of depression and disease requires addressing the root causes with appropriate sun exposure, gut-supporting probiotics, deep sleep, stress management and mitochondrial support

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