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Dr. Joseph Mercola - Take Control of Your Health

Endotoxin/LPS Is a Major Driver of Blood Clotting, Sepsis, Heart Attacks, and Strokes

19 Nov 2025

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Endotoxin, a toxic molecule released by bacteria in your gut, enters your bloodstream and directly triggers blood clot formation — even in people with no signs of infection or heart disease Researchers have shown that certain bacterial types, such as E. coli, are especially effective at setting off your body's clotting response, mimicking what happens during sepsis and other life-threatening events Everyday habits that weaken your gut barrier — including eating seed oils, ultraprocessed foods, and alcohol, or living under chronic stress — make endotoxin exposure common, keeping your blood in a "primed" state to clot Chronic, low-grade exposure to bacterial toxins links gut health to cardiovascular problems, explaining why heart attacks, strokes, and clotting disorders often strike people who appear healthy Supporting your gut with easy-to-digest foods, antioxidants like niacinamide and vitamin E, and natural binders such as raw carrot salad or activated charcoal helps neutralize endotoxin and keep your blood flowing freely

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