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Dr. Joseph Mercola - Take Control of Your Health

Exercise Rewires Your Biology to Improve Energy and Metabolic Health

06 Dec 2025

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Exercise switches on waves of genes, proteins and metabolites that boost energy production, repair tissues and stabilize blood sugar, helping you feel more focused and resilient Endurance and strength training activate different molecular pathways, allowing you to choose routines that match your goals for stamina, fat burning or metabolic control Movement improves the signals your bloodstream uses to coordinate immunity, inflammation and stress responses, which supports steadier moods and better overall health Your muscles release tiny molecular "packages" during activity that influence distant organs like your brain and liver, creating whole-body benefits you can't get from sitting still Short, consistent bouts of movement throughout the day reinforce healthier cellular signaling, making it easier to maintain energy, manage weight and stay metabolically flexible

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