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Dr. Joseph Mercola - Take Control of Your Health

Obesity-Linked Metabolic Stress in Young Adults May Trigger Early Brain Changes

25 Dec 2025

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Early signs of brain damage linked to obesity are already showing up in young adults, decades before symptoms like memory loss or confusion begin Having low levels of choline, a nutrient most people don't get enough of, is strongly connected to inflammation, liver stress, and neuron injury in people with obesity Women are especially vulnerable to brain-related effects of metabolic stress, as they tend to have significantly lower choline levels than men A major brain imaging study confirmed that obesity directly causes brain shrinkage, white matter damage, and reduced cognitive performance — not just a correlation Simple lifestyle shifts like eating more choline-rich foods, cutting seed oils, moving daily, and prioritizing sleep can help repair and protect your brain long before problems show up

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