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Dr. Joseph Mercola - Take Control of Your Health

Say Goodbye to Joint Pain with Vitamin K2

05 Mar 2025

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Story at-a-glance Osteoarthritis results from cartilage deterioration due to genetic, metabolic and inflammatory factors, causing bone friction, pain, stiffness and bone spur formation that impair joint function Studies show boosting vitamin K2 intake supports joint health by regulating calcium metabolism, reducing inflammation, boosting cartilage integrity and activating proteins like GPX4 to protect cartilage cells from damage Elevated levels of vitamin K-dependent proteins like Gla-rich protein (GRP) and matrix Gla protein (MGP) in osteoarthritic joints suggest their protective role against harmful calcium deposits and their use as diagnostic markers Insufficient vitamin K impairs protein activation, allowing calcification, inflammation and cartilage damage to progress unchecked, exacerbating osteoarthritis symptoms and joint degeneration Increasing vitamin K2 intake through foods, supplements and healthy lifestyle changes offers a powerful approach to preserving joint health, reducing inflammation and slowing osteoarthritis progression

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