#48: clonazepam (Klonopin) | Treats Seizure & Panic Disorders, Off-Label for Anxiety, RLS, Sleep Terrors, & More!

Clonazepam is an anticonvulsant benzodiazepine also known as Klonopin. The main indications are for seizure disorder and panic disorder. There are many off label indications such as for anxiety, sleep terrors, sleepwalking, Tourette's syndrome, and RLS. The treatment range for seizure or panic disorders is between 0.5-5 mg PO bid-tid respectively. The mechanism of action is unknown but believed to be a result of GABA activity enhancement. The onset of action is between 20-40 minutes. The time to peak is between 1-4 hours. There are several black box warnings. The first is for the risk of concomitant opioid use; the next is for addiction, abuse, and misuse; and the last is for dependence & withdrawal reactions. Exercise extreme caution for activities that require coordination such as driving and operating machinery.  Go to DrugCardsDaily.com for episode show notes which consist of the drug summary, quiz, and link to the drug card for FREE! Please SUBSCRIBE, FOLLOW, and RATE on Spotify, Apple Podcasts, or wherever your favorite place to listen to podcasts are. The main goal is to go over the Top 200 Drugs with the occasional drug of interest. Also, if you’d like to say hello, suggest a drug, or leave some feedback I’d really appreciate hearing from you! Leave a voice message at anchor.fm/drugcardsdaily or find me on twitter @drugcardsdaily

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