New Primary Aldosteronism – Endocrine Society 2025 Guidelines; Bonus Summary Episode 5

This bonus summary episode distills the Endocrine Society’s 2025 guideline updates on primary aldosteronism into high yield pearls for clinical practice and board preparation. Key topics include:• Broad screening for hypertensive patients regardless of potassium status• Diagnostic evaluation with the aldosterone to renin ratio• Selective use of suppression testing and updated terminology• Adrenal vein sampling (AVS) as the gold standard for lateralization• Surgical vs. medical management based on disease laterality• Mineralocorticoid receptor antagonist therapy, titration, and renin response• Cortisol cosecretion testing and its role in surgical planning• Individualized treatment strategies to improve cardiovascular and metabolic outcomes

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