EnergyMD Podcast
Perimenopause, Blood Sugars, GLP-1 Agonists and Weight Gain with Jennifer Pfleghaar, DO
29 Oct 2025
In this episode, Evan H. Hirsch, MD speaks with Dr. Jennifer Pfleghaar, DO, to unpack the often-misunderstood transition of perimenopause and how it connects to blood sugar issues, weight gain, GLP-1 medications, and chronic fatigue. Dr. Jen Pfleghaar is a double board-certified physician in Emergency and Integrative Medicine who helps people heal by getting to the root cause. A graduate of Lake Erie College of Osteopathic Medicine and fellowship-trained at the Andrew Weil Center for Integrative Medicine, she's passionate about aligning body, mind, and spirit with God's design. After overcoming Hashimoto's herself, Dr. Jen founded Healthy by Dr. Jen and now empowers others through her virtual practice, bestselling book Eat. Sleep. Move. Breathe., and her podcast The Integrative Health Podcast with Dr. Jen. She lives in Tennessee with her husband, four kids, and a lively flock of chickens. In this episode, you'll learn: The truth about perimenopause & why it's starting earlier for many women How cortisol and insulin resistance accelerate hormonal imbalance Signs you're in perimenopause (even if your labs are "normal") When to use bioidentical progesterone or estriol, and when not to How to sync workouts and eating with your menstrual cycle Why synthetic hormones and pellets may be doing more harm than good How GLP-1 agonists like semaglutide should be used for women Why lifestyle and muscle-building matter more than ever during this phase Dr. Jen's Website: https://www.healthybydrjen.com Check her guide ''Peptides for Motherhood'': https://www.healthybydrjen.com/peptides-for-motherhood-bonus-summit . We help you resolve your Long Covid and Chronic Fatigue (ME/CFS) by finding and fixing the REAL root causes that 95% of providers miss. Learn about these causes and how we help people like you, Click Here. Do you have fatigue, brain fog, shortness of breath, muscle pain, or other strange symptoms? You might have Long Covid. Take our free quiz to find out if Long Covid is behind the mystery symptoms you're experiencing, Click Here. For more information about Evan and his program, Click Here. Prefer to watch on Youtube? Click Here. Please note that any information in this episode is for educational purposes only and does not constitute medical advice.
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