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EP Edge Journal Watch

EP Edge Journal Watch: Critical Analysis: AQUATIC Trial — AF + CAD: Impact on Antithrombotic Strategy (NEJM October 2025)

10 Nov 2025

Description

In this special EP Edge Journal Watch episode, Dr. Niraj Sharma delivers a critical analysis of the landmark AQUATIC Trial, published in the New England Journal of Medicine (October 2025). This pivotal study explores optimal antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD) — balancing ischemic protection with bleeding risk.Dr. Sharma dissects trial design, outcomes, and clinical implications, comparing AQUATIC with AUGUSTUS, AFIRE, and AST-Efficient trials, and provides practical insights for real-world decision-making.Stay tuned for concise, evidence-driven interpretation — where every data point translates into better patient care.EP Edge Journal Watch Podcast — From Data to Decision in Cardiac Electrophysiology.

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