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Short Wave

The First Woman To Get A New Kind Of Kidney Transplant

Fri, 20 Dec 2024

Description

Towana Looney became the first living person in the world to get a kidney from a new kind of genetically modified pig last month. Health correspondent Rob Stein got exclusive access to be in the operating room.Towana is a 53-year-old grandmother from Gadsden, Ala. She's been on dialysis for four hours a day, three days a week since 2016. Her immune system would reject a human kidney. So the Food and Drug Administration made an exception to its usual clinical study requirements to allow Looney this new kind of pig kidney. But the procedure is controversial. Interested in more environmental stories? Email us at [email protected]. We'd love to hear from you!Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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Transcription

Chapter 1: What is the groundbreaking kidney transplant discussed in this episode?

0.785 - 4.349 Regina Barber

You're listening to Shortwave from NPR.

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6.171 - 12.599 Regina Barber

Hey Shortwavers, Regina Barber here and I'm here with my colleague, NPR health correspondent and awesome guy, Rob Stein. Hey Rob.

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13.14 - 13.68 Rob Stein

Hey Gina.

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14.001 - 17.365 Regina Barber

I hear that you've been working on this really interesting story for the past year.

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17.952 - 33.964 Rob Stein

Yeah, yeah. I've been following the developments of a biotech company called Revivacor that's been moving towards a very ambitious goal, and that is to use cloned, genetically modified farm animals to provide organs for transplants for humans.

34.349 - 38.293 Regina Barber

Okay, so you're saying farm animals. So there's like a farm just full of cloned animals.

38.774 - 58.835 Rob Stein

Yeah, yeah. In fact, I went to visit this farm. I drove down a road through the Blue Ridge Mountains in southwest Virginia to visit the Rivercore Farm back in February. This farm, it has like 22 buildings and around 300 pigs. We had to change into hospital scrubs before going inside to protect the pigs.

59.095 - 75.948 Rob Stein

They're really careful to make sure visitors don't bring in any pathogens that could infect the pigs. When we went into the buildings, we stepped into these tubs of disinfecting fluid to sterilize our boots. And then I got to see these cloned, genetically modified adult female pigs.

75.968 - 78.35 Unidentified Speaker (Brief Interjection)

Do you want to hold one? No.

Chapter 2: Who is Tawana Looney and why is her case significant?

Chapter 3: What are genetically modified pigs and how do they relate to organ transplants?

148.376 - 169.814 Rob Stein

Yeah, I was inside the OR for the entire operation. And, you know, Gina, this is, I should say, very controversial in a lot of ways. I talked to bioethicists and scientists who have a lot of concerns, you know, concerns about the pigs, about the patients themselves who are desperate for anything, and even the possibility that this could cause a pandemic by spreading pig viruses to people.

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173.618 - 185.987 Regina Barber

So today on the show, the first living person to receive a new kind of genetically modified pig kidney and what that could mean for the future of transplant medicine. You're listening to Shortwave, the science podcast from NPR.

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194.81 - 211.118 Emily Kwong

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213.079 - 228.74 Regina Barber

Hey, short wavers. Emily Kwong here. Believe it or not, the year is almost over. And as we are reflecting on 2024, we're thinking about the hundreds of podcast episodes we've brought you this year. I mean, episodes about big things like climate change, nuclear energy, COVID.

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229.48 - 249.664 Regina Barber

And episodes about weird and wonderful things like sea cucumbers, the biology of memory, the science of skincare trends you see on TikTok. And episodes about stuff we just can't stop obsessing over. I'm looking at you, naked mole rat succession war. Now is the time of year when we reflect on all that work and ask you to support it.

250.424 - 263.452 Regina Barber

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264.443 - 285.672 Regina Barber

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286.332 - 306.779 Regina Barber

Whether you've been with us from the very start or you're listening this week for the first time, supporting public media means you're part of a community of people who are curious about the world. We're honestly so proud to have served the public media community these past five years. Let's keep it going, but it can only be done with your help. So join NPR Plus today at plus.npr.org.

307.52 - 308.0 Regina Barber

Thanks so much.

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