
I'll teach you how to become the media's go-to expert in your field. Enroll in The Professional's Media Academy now: https://www.professionalsmediaacademy.com/Fact Check #1: 44:50 - https://www.youtube.com/watch?v=W_ZGhRZee9AFact Check #2: 1:14:49 - https://youtu.be/OzvtIXiHjqg00:00 Intro02:20 How He Started08:00 Who Has Access?13:39 Does Prenuvo Actually Save Lives?23:10 Scans Causing Anxiety / False Positives31:46 Harms Of Scanning39:30 False Promises Of Scanning46:52 AI Spine Research56:45 The Psychology Of Good Health1:00:38 Prenuvo vs. Traditional System1:09:53 Brian Johnson / Longevity1:15:15 Biased Research1:25:47 Kim Kardashian's Endorsement1:32:53 Changes He MadeHelp us continue the fight against medical misinformation and change the world through charity by becoming a Doctor Mike Resident on Patreon where every month I donate 100% of the proceeds to the charity, organization, or cause of your choice! Residents get access to bonus content, an exclusive discord community, and many other perks for just $10 a month. Become a Resident today:https://www.patreon.com/doctormikeLet’s connect:IG: https://go.doctormikemedia.com/instagram/DMinstagramTwitter: https://go.doctormikemedia.com/twitter/DMTwitterFB: https://go.doctormikemedia.com/facebook/DMFacebookTikTok: https://go.doctormikemedia.com/tiktok/DMTikTokReddit: https://go.doctormikemedia.com/reddit/DMRedditContact Email: [email protected] Producer: Doctor MikeProduction Director and Editor: Dan OwensManaging Editor and Producer: Sam BowersEditor and Designer: Caroline WeigumEditor: Juan Carlos Zuniga* Select photos/videos provided by Getty Images *** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional **
Chapter 1: What is a full body MRI scan?
My experience had been pretty underwhelming in the context of preventive care. It was a checkout that was absent any real unique insight that I didn't really know myself. I wanted to go a layer deeper.
Celebrities like Kim Kardashian have jumped on the wave of support of a new kind of preventative care.
Chapter 2: How did Andrew Lacey start Prenuvo?
It comes with a hefty price tag. We're talking about Pernuvo's full-body MRI scans.
One could hypothesize that I'm a visitor from another planet, and on my planet, we screen everyone. You know, I take you back to my plant and say, well, let me propose to you that you don't screen anyone. My population would laugh you off the planet.
Why are there no major United States organizations that are recommending this?
I don't think there's any evidence that consumers consider themselves harmed by these screenings.
The burden should fall when you're testing healthy people to prove that it causes benefit rather to prove that it causes harm. Welcome to the Checkup Podcast. Today, my guest is Andrew Lacey, CEO of Pernuvo, a company that's at the forefront of whole body MRI scanning, a technology that aims to catch potential health issues before they become serious problems.
You may have recently seen the company's technology in headlines or on Kim Kardashian's Instagram, spurring excitement, intrigue, and even some controversy. You see, major medical organizations, including the American College of Radiology and the United States Preventive Service Task Force do not recommend routine whole body scans for people without symptoms or specific risk factors.
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Chapter 3: Who can access Prenuvo's MRI scans?
There are concerns about false positives, unnecessary follow-up procedures, the cost effectiveness, and most importantly, if the proposed benefits actually outweigh the risks. Despite that, advocates of this technology argue that those concerns are overblown and that the scans can provide peace of mind and potentially detect conditions early when they're most treatable.
In today's conversation, we dive right into addressing those controversies head on, as well as the science of the scans and how Pernuvo is handling being at the forefront of this emerging field. As a reminder, if you hear this sound,
That means there is a fact check that is linked down below to a separate unlisted video that you could click on during or after the presentation to just get a bit more info.
Do you know this one friend who just comes out of bed in the morning and then doesn't come out of a grin? Who is even in front of the first coffee, shamelessly well-groomed and shines around the bed with the morning sun? Terrible. Disgusting. How can you just be so... Restless?
Very simple. Train your sleep and become a morning person. With the Galaxy Watch 7 or the Galaxy Ring and the Samsung Health app.
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Chapter 4: Can Prenuvo's scans save lives?
You're a business person. You were working, starting multiple businesses. I believe it was four at the time. And then you found a passion in treating, talking about, and fixing the healthcare space. How did you get there?
Well, the starting point really was I was a serial entrepreneur for probably the first 20 years of my career. And I was a typical entrepreneur. I didn't sleep enough. I didn't eat enough.
I didn't exercise enough.
I had a lot of stress. Some of those things, by the way, are still true because I am still an entrepreneur. But I remember one day just waking up and looking in the mirror and saying, hey, we're doing this to make the world a better place. What guarantees do I have that I'm going to be around for this future that I'm trying to create? And in that moment, I had just taken my car to a new body shop.
And my car was asymptomatic.
So you were going for a preventive checkup.
I was going for a preventive checkup of my car. And what I got back from the shop, maybe they all do it this way now, but I got a 30-page report of every component in my car, the engine, the transmission, the clutch, the brake pads, the wiper fluid, what was running low, where were the brake pads wearing,
How was the way I was riding the clutch sort of like affecting the wear and tear on that component? How I could drive my car better? What needed to replace now? What could be replaced in the future? What should I watch? And I just had this like moment of like complete dissonance.
Why on earth do I have this like 30 page report about my car and really understand deeply how it's performing and how it's tracking in its health. And I don't have that same picture for myself. When I look in the mirror, my understanding of my health was sort of skin deep. Interesting. And that really started me on this journey.
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Chapter 5: What are the psychological effects of scanning?
At that time, were you having a relationship with a primary care doctor doing checkups or not really?
Not really. I mean, I had a primary care, like most people that have a primary care doctor.
It's not most people, sadly. I wish more people had a primary care doctor.
But my experience had been pretty underwhelming in the context of preventive care. So yes, if I presented with a flu or some sort of acute problem, usually I could get some relief from visiting a physician. But my annual physical usually went along the following lines. Tell me about what you do. I'm stressed. I don't eat enough. I don't exercise.
And the answer was generally after some sort of cursory pushing or prodding on my abdomen, well, maybe you should think about, you know, working on your stress levels, eating better and exercising more.
So lifestyle modifications.
Which I'm not saying is the wrong answer, but it was also sort of, it was like, it was a checkout that was absent any real unique insight that I didn't really know myself. You know, I wanted to go a layer deeper. Okay. And that was the journey that I went on search for an answer for. And that took me of all places from Silicon Valley up to Vancouver, Canada.
Wow. Okay. How did that search form? Were you Googling?
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Chapter 6: What are the harms of full-body scanning?
Were you talking to friends? Talking to friends. Okay. And I had a friend of mine that had gone to TED, which is in Vancouver, and with her mother the year before, and they had heard about a doctor that was doing an early precursor to what is now the Prudigo scan.
And she had gone with her mother and they had diagnosed a quite large aneurysm in her mother that in the week she got treated, her sister, so the auntie of my friend, had passed away from a burst aneurysm. So I just thought it was crazy that this could happen.
Now, someone in the medical profession like yourself, probably that's not so unusual, but for a lot of consumers, I mean, a lot of us, we don't walk around thinking this could happen to me one day without warning.
And that uncertainty is scary.
Right. And so I got on a plane and went and got one of these scans. And back then, you used to sit down with a radiologist immediately after the scan and go through the results. It was kind of scary. And I was scared doing it. What might we find?
I went out for a nice meal the night before, had a nice glass of wine and said, I'm going to enjoy today because tomorrow my life's probably going to change. I'm going to get a full accounting of the abuse that I had sort of subjected my body to. And I sat down with the radiologist and I learned, A, I wasn't dying of anything that I didn't know about.
B, I had some really clear insights into how the way I was living my life was sort of impacting the physiology of my body. And most importantly and most profoundly and the hardest thing to explain was I got this tremendous feeling of peace of mind. And I came back to San Francisco and that was the thing that stuck with me.
You know, it was sort of, I don't know if maybe some of your viewers have ever been skydiving or something. You sort of like feel like you're bouncing around with a bit of adrenaline for a couple of weeks afterwards. Or you see the world with a little bit more color. That's sort of how it felt.
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Chapter 7: How does Prenuvo compare to traditional medical systems?
Like you got a new lease on life.
I got a new lease on life. And I sort of like, you know, I would get a headache and rather than being concerned about what it might be, just realizing it was a headache or a stomach pain was because I ate something bad. And that voice that had been there, not always consciously, but always I would say subconsciously was quiet for a period of time. And I thought that was incredible.
And so I couldn't shake the idea that I had seen something that was potentially the future of the way we should do practice medicine. So two weeks later, I went back and didn't leave for three or four months and sat down with that team and met a bunch of consumers and formed an opinion that this is something that the world deserves to have access to.
Why do you think we didn't have access to it at that point? Or actually, we sort of still don't in many respects, right? Unless we're going to a private institution to get it. It's not covered by insurance. It's not in the medical establishments.
Yeah, I mean, you can do them. So here, I guess at Memorial Sloan Kettering or, you know, in Boston and Harvard or Stanford in the Bay Area, you can do these scans. They're often offered to people that have a cancer predisposition syndrome. So a syndrome like lupramine, fancomia anemia.
Multiple endocrine neoplasia syndrome.
And they are covered by insurance, but they're billed at something like $50,000 to $100,000. They take three hours and they often require general anesthetic just for you to tolerate the procedure of lying in the machine.
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Chapter 8: What are the implications of celebrity endorsements?
So what was different here was, you know, solving for a unique combination of hardware, image acquisition protocols to bring these scans down to under an hour so it could be offered in a sort of comfortable consumer context. And that's what this team had first done up there in Canada.
Mm-hmm. And how does the current Pernuvo scan decide who is a patient or who is a candidate? Like, for example, I'm very pro being preventive when it comes to healthcare. And there's many tests that I offer in my practice that are sort of agreed upon screening programs that we do. colon cancer screening, pap smears for cervical cancer, blood tests for screening for diabetes.
And for the audience, when we say screening, that's generally asymptomatic people, meaning no symptoms recommended to everybody to try and catch this problem. And in the past, within at least my healthcare space, we've kind of,
titrated, for lack of a better term, back and forth between not scanning too many people, making sure we're scanning the right demographics so that we're not creating false positives, over-diagnosis, over-treatment. How does that play a role in the PernuvoScan world?
Well, I think it's important to really understand the history of some of those tests that you just mentioned. So, you know, a pap smear, which now most physicians would consider part of their standard of care screening, that was first sort of clinically validated in 1910. And it did not become part of standard practice until the 40s or 50s.
Mammogram, you know, some of the first clinical studies were in the 60s and it was not covered by insurance until the 90s. You know, low dose CT screening for smokers took 20 years. PSA, maybe that's a little more controversial, but still took 15, 20 years to be covered.
So what happened in that intervening period was we saw clinical use of these tools and that clinical use very much made the evidentiary case for these to be eventually sort of adopted as part of standard of care. And I think that's the journey that the whole body screening with MRI, the multi-parametric approach that we're doing at Prenuvo, that's the journey that it's on.
So right now, would you say the people who are getting scans are people who were trying to create clinical validity for the future to be used in insurance programs? Like they're almost in a clinical experiment? Yeah.
Well, I wouldn't say that. It's a mistake to think of this as a test. This is a clinical practice that we run. So we have a team now of 50 radiologists that collectively read these scans. We have head of specialties that work with the company. Many of these people have Ivy League education. They're all board certified radiologists in the states in which they practice.
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