这篇文章详细介绍了古代欧亚大陆人类病原体的时空分布。研究人员通过筛选1313名古代欧亚人37,000年历史的鸟枪法测序数据，绘制了一幅基于考古遗传学的病原体时空地图，揭示了古代细菌、病毒和寄生虫DNA的广泛存在。研究发现，已知的人类病原体在这些样本中大量出现，并且许多是首次在古代人类遗骸中被发现。特别值得注意的是，人畜共患病原体在大约6,500年前才被检测到，并在约5,000年前达到高峰，这与牲畜驯化的广泛普及相吻合，表明生活方式的改变导致了传染病负担的增加。研究进一步指出，这些病原体的传播在随后的几千年里显著增加，这与欧亚大草原游牧民族的迁徙同步，为理解传染病如何塑造人类历史和基因组提供了直接证据。References: Sikora, M., Canteri, E., Fernandez-Guerra, A. et al. The spatiotemporal distribution of human pathogens in ancient Eurasia. Nature (2025). doi.org
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