这些研究主要探索肠道微生物及其代谢产物在衰老和心血管疾病中的作用。第一篇文章讨论了胆汁酸石胆酸如何通过模拟限食的效果来延缓衰老。另两篇文章则聚焦于肠道细菌产生的一种名为咪唑丙酸（ImP）的分子，揭示了其促进动脉粥样硬化斑块形成的机制。其中一篇详细阐述了ImP如何通过特定受体和免疫细胞激活炎症反应，从而加速动脉粥样硬化，并且提出阻断ImP-I1R轴可能成为治疗心血管疾病的新途径。这些来源共同强调了微生物-宿主相互作用在健康和疾病发展中的重要性。References: https://www.nature.com/articles/d41586-025-02060-5 Mastrangelo, A., Robles-Vera, I., Mañanes, D. et al. Imidazole propionate is a driver and therapeutic target in atherosclerosis. Nature (2025). doi.org https://www.nature.com/articles/d41586-024-03030-z https://www.nature.com/articles/d41586-024-04062-1
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