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第2713期:Babies' first bacteria could prevent infection

13 Jul 2025

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We come out of the womb sterile, but that doesn't last for long. All the nooks and crannies of the human body soon become home to microbial life. In this study, scientists took stool samples from 1,000 newborns. Those first colonised by Bifidobacterium longum were half as likely to end up in hospital with a lung infection than those with different starter bacteria.我们从子宫里出来时是无菌的,但这种状态不会持续太久。人体的每个角落和缝隙很快就会成为微生物群落的家园。在这项研究中,科学家们采集了 1000 名新生儿的粪便样本。他们发现那些体内最早被长双歧杆菌占领建立菌群的婴儿,其日后因肺部感染住院的几率仅为携带其它初始菌群婴儿的一半。It's the first time the way our microbial ecosystem forms has been shown to reduce infections. The researchers at UCL and the Sanger Institute said it was a phenomenal finding. Early life is a critical period for developing the immune system and these latest findings could lead to the development of new therapies similar to a probiotic yoghurt to give good bacteria to babies.↳这是首次有研究显示我们体内微生物生态系统的形成方式可以减少感染。来自伦敦大学学院和桑格研究所的研究人员们称这一发现意义重大。生命早期是免疫系统发育的关键时期,这些最新研究成果可能会促进新疗法的开发,类似于益生菌酸奶那样,为婴儿提供有益细菌。

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