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Aaron Boster

👤 Person
887 total appearances

Appearances Over Time

Podcast Appearances

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

It's doing an old school neuro exam.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

You know, the neuro exam dates back to, you know, ancient Chinese history, and it's a really inaccurate thing.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now, in the 80s, this machine came out, which was really exciting, and it's called the MRI.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And it's a completely revolutionized diagnosis.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

It became gospel in 2001, and it's been revised to make it easier and faster and faster to use the MRI to make a quick diagnosis.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And so we get an MRI of the brain and the spine.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And if we see spots in certain locations, we can diagnose MS right there.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

If not, then we can old school wait for another attack, which is never the goal.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

We can repeat the scans at intervals looking for new spots, or we can depend upon a lumbar puncture, spinal tap.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now, if you're listening in Europe, most people across the pond, they're all tapped.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Here in the United States, that happens a lot less frequently, but you can see changes on the spinal tap on the CSF, which would then help cinch a diagnosis.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

We have desperately needed better biomarkers in the field of multiple sclerosis now for some time.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now a biomarker is simply a measurement which teaches us something about the human being.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And the most common biomarker in the MS space has been and continues to be the MRI.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

So we're getting a picture of brain and spine structure.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

There's a test which has been developed and now been validated in several very well done trials, which is a blood test.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And a high number on this test correlates with concern for disease activity, particularly on the MRI.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

A low number suggests disease stability.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now, this test is approved by the American FDA.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

It's starting to be increasingly used in MS consultations.