Aditya Bagrodia

You know, while I think we like to get those durations of ADT in for the intermediate risk patients and for the high risk patients, it's kind of a little bit of a conversation, right? If they're completely miserable and life is not worth living, then it's not like we're going to strap you down and get you two years in.

You know, while I think we like to get those durations of ADT in for the intermediate risk patients and for the high risk patients, it's kind of a little bit of a conversation, right? If they're completely miserable and life is not worth living, then it's not like we're going to strap you down and get you two years in.

It might be, all right, you know, you're high risk, let's really try to get a year in and, you know, we can horse trade after that. Okay. So, yeah, you kind of mentioned, you know, there's injections, there's Degrelix, Erigolix, there's good old-fashioned ADT. Antiandrogens, do those have much of a role anymore?

It might be, all right, you know, you're high risk, let's really try to get a year in and, you know, we can horse trade after that. Okay. So, yeah, you kind of mentioned, you know, there's injections, there's Degrelix, Erigolix, there's good old-fashioned ADT. Antiandrogens, do those have much of a role anymore?

It might be, all right, you know, you're high risk, let's really try to get a year in and, you know, we can horse trade after that. Okay. So, yeah, you kind of mentioned, you know, there's injections, there's Degrelix, Erigolix, there's good old-fashioned ADT. Antiandrogens, do those have much of a role anymore?

Yeah, I mean, I would tend to agree. And I think in those contexts, those kind of extreme contexts, cord compression, saddle paresthesias and so forth, it's pretty easy to use a GNRH antagonist and just kind of be done with it and get castrate, you know, in the order of hours. You know, I think that's also a context where bilateral orchiectomy still, you know, remains in the toolkit.

Yeah, I mean, I would tend to agree. And I think in those contexts, those kind of extreme contexts, cord compression, saddle paresthesias and so forth, it's pretty easy to use a GNRH antagonist and just kind of be done with it and get castrate, you know, in the order of hours. You know, I think that's also a context where bilateral orchiectomy still, you know, remains in the toolkit.

Yeah, I mean, I would tend to agree. And I think in those contexts, those kind of extreme contexts, cord compression, saddle paresthesias and so forth, it's pretty easy to use a GNRH antagonist and just kind of be done with it and get castrate, you know, in the order of hours. You know, I think that's also a context where bilateral orchiectomy still, you know, remains in the toolkit.

All right, so side effects. You know, my usual, and it's always a little bit tricky, especially when you're talking to people with a new diagnosis of prostate cancer and they're a candidate for surgery or radiation and you're talking about hormones. I almost feel a little bit bad because when you run through the litany of stuff, it sounds so awful that...

All right, so side effects. You know, my usual, and it's always a little bit tricky, especially when you're talking to people with a new diagnosis of prostate cancer and they're a candidate for surgery or radiation and you're talking about hormones. I almost feel a little bit bad because when you run through the litany of stuff, it sounds so awful that...

All right, so side effects. You know, my usual, and it's always a little bit tricky, especially when you're talking to people with a new diagnosis of prostate cancer and they're a candidate for surgery or radiation and you're talking about hormones. I almost feel a little bit bad because when you run through the litany of stuff, it sounds so awful that...

you know, people are just like, there's no way I'm going to do that. You know, there's going to be loss of muscle mass, increase in fat mass, or maybe some cognitive impact, some cardiovascular risk, osteoporosis, weight gain, loss of libido, erectile dysfunction, fatigue. I mean, do you like run through this?

you know, people are just like, there's no way I'm going to do that. You know, there's going to be loss of muscle mass, increase in fat mass, or maybe some cognitive impact, some cardiovascular risk, osteoporosis, weight gain, loss of libido, erectile dysfunction, fatigue. I mean, do you like run through this?

you know, people are just like, there's no way I'm going to do that. You know, there's going to be loss of muscle mass, increase in fat mass, or maybe some cognitive impact, some cardiovascular risk, osteoporosis, weight gain, loss of libido, erectile dysfunction, fatigue. I mean, do you like run through this?

Yeah, I think that's clutch. And, you know, the body dysmorphism, I don't know if I mentioned, but the gynecomastia that can be very troublesome to patients. And, you know, of course I do too. And I don't know necessarily why, but I feel like there's still this like surgery, radiation kind of situation. And I always feel like a little bit bad, like bad mouthing the other option. Yeah.

Yeah, I think that's clutch. And, you know, the body dysmorphism, I don't know if I mentioned, but the gynecomastia that can be very troublesome to patients. And, you know, of course I do too. And I don't know necessarily why, but I feel like there's still this like surgery, radiation kind of situation. And I always feel like a little bit bad, like bad mouthing the other option. Yeah.

Yeah, I think that's clutch. And, you know, the body dysmorphism, I don't know if I mentioned, but the gynecomastia that can be very troublesome to patients. And, you know, of course I do too. And I don't know necessarily why, but I feel like there's still this like surgery, radiation kind of situation. And I always feel like a little bit bad, like bad mouthing the other option. Yeah.

You know me well enough that it's like, you should just understand all your options very, very well and then pick the one that suits you better. So maybe I subconsciously downplay some of the adverse effects that I don't want it to come across as biased, which is silly. You know, I think it's an...

You know me well enough that it's like, you should just understand all your options very, very well and then pick the one that suits you better. So maybe I subconsciously downplay some of the adverse effects that I don't want it to come across as biased, which is silly. You know, I think it's an...

You know me well enough that it's like, you should just understand all your options very, very well and then pick the one that suits you better. So maybe I subconsciously downplay some of the adverse effects that I don't want it to come across as biased, which is silly. You know, I think it's an...