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Alex McColgan

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
21005 total appearances

Appearances Over Time

Podcast Appearances

Astrum Space
What Would Alien Life Look Like?

One that doesn't require enzymes.

Astrum Space
What Would Alien Life Look Like?

One driven in part by the same physical pressures as fatty acids forming a cell-like structure.

Astrum Space
What Would Alien Life Look Like?

A mechanism that could have introduced information to protocells.

Astrum Space
What Would Alien Life Look Like?

You see, different RNA bases can encode specific amino acids.

Astrum Space
What Would Alien Life Look Like?

This means that a random string of RNA in early protocells could have produced a non-random string of amino acids, which could have conferred an advantage to the protocell containing it.

Astrum Space
What Would Alien Life Look Like?

Perhaps the amino acids stabilized the membrane.

Astrum Space
What Would Alien Life Look Like?

and it would have been more likely to survive and divide, potentially reproducing that information and passing it on.

Astrum Space
What Would Alien Life Look Like?

So now we have a great primordial soup of molecular potential.

Astrum Space
What Would Alien Life Look Like?

We have the thermodynamic encouragement for life, self-dividing cell walls and short RNA strands that could have encoded functional amino acids.

Astrum Space
What Would Alien Life Look Like?

How can we get past this primordial soup of small molecules for life to emerge?

Astrum Space
What Would Alien Life Look Like?

Well, we also need the one mechanism that is crucial to all theories.

Astrum Space
What Would Alien Life Look Like?

Selection.

Astrum Space
What Would Alien Life Look Like?

Without selection pressures, in 14 billion years, molecular complexity wouldn't have moved much past basic molecules like these, let alone a complex enzyme, because you'd be relying on random processes with very low probabilities.

Astrum Space
What Would Alien Life Look Like?

Very much like shaking a bag of Lego bricks together for a few years and expecting a perfectly formed Death Star to pop out.

Astrum Space
What Would Alien Life Look Like?

As the size of a molecule grows, the space of possible configurations grows absurdly quickly, and the probability that even one specific molecule can be made in a useful quantity by chance falls to near zero.

Astrum Space
What Would Alien Life Look Like?

and that's just for one molecule, let alone a gold pocket watch, the creationists may have a point.

Astrum Space
What Would Alien Life Look Like?

Incredibly though, research suggests that the proposed chemical reactions on early Earth were capable of a kind of evolution way before they transitioned to life.

Astrum Space
What Would Alien Life Look Like?

Some chemical reaction pathways can produce molecules that catalyze the pathway itself,

Astrum Space
What Would Alien Life Look Like?

These are known as autocatalytic.

Astrum Space
What Would Alien Life Look Like?

This catalysis increases the flow of resources through one pathway, potentially away from a competing pathway, and therefore increases the first success.