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Alex Ossola

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10011 total appearances
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Podcast Appearances

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

They're currently in trials, and if the drugs work, the companies could be on the verge of the next big market for heart drugs.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

It's valued at as much as $25 billion a year.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Journal reporter Xavier Martinez joins me now with more.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Xavier, lipoprotein A, or LPA, has been difficult to treat for a long time.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Diet and exercise don't really help because it's genetic.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

And other heart drugs like statins can actually raise LPA.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

What's different about these new drugs?

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

You mentioned that these drugs are in trials right now.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

How promising are they looking and what still needs to happen before they can go in front of the FDA for approval?

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Just to be clear on one point here, we know that higher levels of LPA are linked to heart disease.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

But it's not totally clear yet that a drug that then lowers those levels of LPA will help cut the risk of heart disease.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Is that right?

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

That was WSJ reporter Xavier Martinez.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Thanks, Xavier.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Lululemon is making peace with its founder, Chip Wilson.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Wilson is a big shareholder, owning 8.7 percent of Lululemon's shares.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

And he's criticized the leggings company for years, arguing that it's no longer cool and has given up its lead to newer rivals.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

For example, last October on CNBC's Squawk Box, he said that the board was too focused on hitting Wall Street's numbers.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

In December, he launched a proxy fight seeking to overhaul the company's board.

WSJ What’s News
A New Generation of Drugs Could Lower Heart Attack Risk for Millions

Now, Lululemon and Wilson have reached a deal.