Alexis Fernandez-Preiksa

It's a sedative hypnotic drug.

So it works as a central nervous system depressant.

And a lot of the drugs that I talk about, especially when you're treating things like anxiety or insomnia or other related things, work as a central nervous system depressant.

You are reducing activity in the CNS instead of being something that's going to increase activity.

So you're depressing that activity and you're enhancing signaling at the GABA-A receptor complex.

I'll go into that in a second.

But in like broad terms, it's got similar effects to alcohol, barbiturates and benzodiazepines as well.

So to break it down, GABA is the brain's major inhibitory neurotransmitter.

It basically is telling the neurons to stop firing or fire less or to calm down.

Methylqualone is amplifying that signaling, this inhibitory signaling of GABA.

And then that creates sedation, muscle relaxation.

It lowers anxiety.

It reduces inhibition.

And then it also increases sleepiness.

So you want to look at it as it's kind of turning down the excitability in your neurons.

We've got relaxation, euphoria, slowed reaction time, also impaired memory, but also reduced anxiety.

And at much higher doses, you've got respiratory depression as well, which is not a good thing.

Now, if you guys ever watched The Wolf of Wall Street, you see when he takes all the quaaludes and gets really fucked up.

And what's not funny or it's not anything, but at the time where quaaludes were such a big recreational drug and when this movie is set and when he was taking all those quaaludes, it had already been pulled off the market.

So it already was just kind of a recreational illegal substance to be taking and it wasn't something that you were just –