Amy Alkon

Just sort of observational studies. They're not science. And so we have a crisis right there. It's not just the reproducibility crisis. It is the crisis in the actual training in the scientific methodology that we've just completely let go of for some reason. Exactly. Before we go further... I want to address the heterogeneity you said in terms of the testosterone replacement therapy.

Just sort of observational studies. They're not science. And so we have a crisis right there. It's not just the reproducibility crisis. It is the crisis in the actual training in the scientific methodology that we've just completely let go of for some reason. Exactly. Before we go further... I want to address the heterogeneity you said in terms of the testosterone replacement therapy.

That is exactly it.

That is exactly it.

Okay, well, then maybe I did that in my head because that is exactly the issue with testosterone is that women are fantastically different in how they respond, particularly to hormones like testosterone. Susan, your story again with testosterone.

Okay, well, then maybe I did that in my head because that is exactly the issue with testosterone is that women are fantastically different in how they respond, particularly to hormones like testosterone. Susan, your story again with testosterone.

They gave her antidepressants and hormone replacement therapies.

They gave her antidepressants and hormone replacement therapies.

You must be in a mood, Susan, right now, because that wasn't what I was, what I was going for was how it affected your vitality and your mood. I'm getting there. I'm getting there.

You must be in a mood, Susan, right now, because that wasn't what I was, what I was going for was how it affected your vitality and your mood. I'm getting there. I'm getting there.

What you said to me at the time was, I feel like a part of me had died and was brought back to life when I was a younger woman. And I thought, oh, that's quite vivid. That's very vivid. But by the same token, Amy, to your point, I know plenty of women who I referred for replacement therapies of various type who respond negatively to testosterone. They lose their hair. They get aggressive.

What you said to me at the time was, I feel like a part of me had died and was brought back to life when I was a younger woman. And I thought, oh, that's quite vivid. That's very vivid. But by the same token, Amy, to your point, I know plenty of women who I referred for replacement therapies of various type who respond negatively to testosterone. They lose their hair. They get aggressive.

They get irritable.

They get irritable.

But Susan, again, it's a heterogeneous spectrum. It's going to be hard to sort that all out.

But Susan, again, it's a heterogeneous spectrum. It's going to be hard to sort that all out.

Yeah, it's individual. The end of one here. End of one. We get it.

Yeah, it's individual. The end of one here. End of one. We get it.

Yeah, if you're picking up a hammer and using the claw and on your friends, I worry about that. But you're absolutely correct. That irritability, that sort of boiling, but it's irritability and misery. There's misery associated with this. And we do a woeful job. This book, your book sounds like on point. It's about time somebody wrote this book.

Yeah, if you're picking up a hammer and using the claw and on your friends, I worry about that. But you're absolutely correct. That irritability, that sort of boiling, but it's irritability and misery. There's misery associated with this. And we do a woeful job. This book, your book sounds like on point. It's about time somebody wrote this book.