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Andrew Pask

๐Ÿ‘ค Speaker
76 total appearances

Appearances Over Time

Podcast Appearances

The Claire Byrne Show
Explaining de-extinction

I mean, this is a plastic-made structure that we then have a special membrane that sits on the inside, which enables the gas exchange.

The Claire Byrne Show
Explaining de-extinction

The chicken still lays the egg for us, right?

The Claire Byrne Show
Explaining de-extinction

So we still get the chicken to lay the egg, but soon after laying, we take that egg and then we will actually break it open and place it into this artificial device.

The Claire Byrne Show
Explaining de-extinction

And from there, we can go through the entire rest of the three weeks of

The Claire Byrne Show
Explaining de-extinction

that a normal chick would take to develop right up until the point when it hatches out of the artificial egg and you've got a healthy living little chick.

The Claire Byrne Show
Explaining de-extinction

Yeah, we made the woolly mice.

The Claire Byrne Show
Explaining de-extinction

Obviously, it's very hard to do genetics on elephants or mammoths if you want to try and make a few edits and see what happens.

The Claire Byrne Show
Explaining de-extinction

It's almost impossible to do something in an animal of that scale.

The Claire Byrne Show
Explaining de-extinction

But we're very good at doing genetic manipulations in mice.

The Claire Byrne Show
Explaining de-extinction

They're really sort of the workhorse for us to understand how our genes regulate the way that we look.

The Claire Byrne Show
Explaining de-extinction

And so a lot of the genes that we identified that were important for making the woolly mammoth woolly, we were able to engineer into mice and to show that we could make a little orange woolly mouse that has that same sort of long, shaggy hair that you would see on a woolly mammoth.

The Claire Byrne Show
Explaining de-extinction

But that lets us know that we're on the right path to making the right edits when we come to engineering our woolly mammoth.

The Claire Byrne Show
Explaining de-extinction

Yeah, well, it's all about understanding how the bits of our DNA actually change the way we look.

The Claire Byrne Show
Explaining de-extinction

And that's something we still don't understand very, very well.

The Claire Byrne Show
Explaining de-extinction

But we're using all of these tools now to really sort of unpack exactly how those mechanisms work so we can engineer these species.

The Claire Byrne Show
Explaining de-extinction

Yeah, well, I think if you make all of the edits that you would need to to recreate that exact MOA genome.

The Claire Byrne Show
Explaining de-extinction

So that's the process we're working on at the moment is sequencing every single bit of the DNA code of how to build a MOA.

The Claire Byrne Show
Explaining de-extinction

And then using that, we identify its closest living relative.

The Claire Byrne Show
Explaining de-extinction

And then we make all of those edits.

The Claire Byrne Show
Explaining de-extinction

We are re-engineering that moa genome.