Andrew Pask
๐ค SpeakerAppearances Over Time
Podcast Appearances
I mean, this is a plastic-made structure that we then have a special membrane that sits on the inside, which enables the gas exchange.
The chicken still lays the egg for us, right?
So we still get the chicken to lay the egg, but soon after laying, we take that egg and then we will actually break it open and place it into this artificial device.
And from there, we can go through the entire rest of the three weeks of
that a normal chick would take to develop right up until the point when it hatches out of the artificial egg and you've got a healthy living little chick.
Yeah, we made the woolly mice.
Obviously, it's very hard to do genetics on elephants or mammoths if you want to try and make a few edits and see what happens.
It's almost impossible to do something in an animal of that scale.
But we're very good at doing genetic manipulations in mice.
They're really sort of the workhorse for us to understand how our genes regulate the way that we look.
And so a lot of the genes that we identified that were important for making the woolly mammoth woolly, we were able to engineer into mice and to show that we could make a little orange woolly mouse that has that same sort of long, shaggy hair that you would see on a woolly mammoth.
But that lets us know that we're on the right path to making the right edits when we come to engineering our woolly mammoth.
Yeah, well, it's all about understanding how the bits of our DNA actually change the way we look.
And that's something we still don't understand very, very well.
But we're using all of these tools now to really sort of unpack exactly how those mechanisms work so we can engineer these species.
Yeah, well, I think if you make all of the edits that you would need to to recreate that exact MOA genome.
So that's the process we're working on at the moment is sequencing every single bit of the DNA code of how to build a MOA.
And then using that, we identify its closest living relative.
And then we make all of those edits.
We are re-engineering that moa genome.