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Ari Daniel

๐Ÿ‘ค Speaker
675 total appearances

Appearances Over Time

Podcast Appearances

Short Wave
Could this vaccine trial mean a future without HIV?

After returning to Johannesburg, she says the official stop work orders arrived from Washington just weeks before the trial was to begin.

Short Wave
Could this vaccine trial mean a future without HIV?

Everything came to a sudden halt.

Short Wave
Could this vaccine trial mean a future without HIV?

All the money was gone.

Short Wave
Could this vaccine trial mean a future without HIV?

And remember Linda Gale Becker from the top of the episode?

Short Wave
Could this vaccine trial mean a future without HIV?

That's the one.

Short Wave
Could this vaccine trial mean a future without HIV?

She says when the funding collapsed, she cycled through the stages of grief.

Short Wave
Could this vaccine trial mean a future without HIV?

But soon, this team of researchers decided that they needed to find a different way forward.

Short Wave
Could this vaccine trial mean a future without HIV?

A period of frantic grant writing began, and finally they got funding from the South African Medical Research Council and the Gates Foundation.

Short Wave
Could this vaccine trial mean a future without HIV?

No, they couldn't raise that much, but they did get about $2.2 million.

Short Wave
Could this vaccine trial mean a future without HIV?

Of course.

Short Wave
Could this vaccine trial mean a future without HIV?

The new grant was focused inside South Africa only.

Short Wave
Could this vaccine trial mean a future without HIV?

And that meant that they had to sacrifice studying how the vaccine might work against different versions of the virus within different African populations.

Short Wave
Could this vaccine trial mean a future without HIV?

Here's Penny Moore again.

Short Wave
Could this vaccine trial mean a future without HIV?

Despite having to reduce the scope of the grant, though, Penny told me that HIV vaccine research is farther along than it's ever been.

Short Wave
Could this vaccine trial mean a future without HIV?

You know it.

Short Wave
Could this vaccine trial mean a future without HIV?

It contains all those samples that those 117 women have donated over the years.

Short Wave
Could this vaccine trial mean a future without HIV?

including why the virus is so skilled at evading our body's defenses.

Short Wave
Could this vaccine trial mean a future without HIV?

But remarkably, in the blood of a few of these women, something pretty special surfaced after they became infected with HIV.

Short Wave
Could this vaccine trial mean a future without HIV?

Penny tells me in her office it's something called a broadly neutralizing antibody.

Short Wave
Could this vaccine trial mean a future without HIV?

Does it wear a cape?