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Aurelia Song

๐Ÿ‘ค Speaker
206 total appearances

Appearances Over Time

Podcast Appearances

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Conflict of interest note.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

During grad school, I worked as a volunteer for the Brain Preservation Foundation for about a year.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

After learning more about brain preservation, I decided to quit as a volunteer and enter the prize myself, with Ken's approval.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

You may notice that some of the references I cite throughout this post attribute my work to my dead name, Robert McIntyre.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Today I go by my chosen name, Aurelia Song.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

That's the end of the list.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

In the lab, Ken Hayworth and the BPF.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

What is the Brain Preservation Foundation?

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Ken Hayworth is a neuroscientist currently working at Janelia Research, part of HHMI, the Howard Hughes Medical Institute.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

In 2010, Ken started the Brain Preservation Foundation and launched the Brain Preservation Prize as a challenge to the neuroscience and cryonics community.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

He wanted to see researchers provide evidence that their preservation could work according to neuroscientifically reasonable standards.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

As a connectomycist, Ken is used to looking at 3D models of brain tissue created with electron microscopy.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

These models are scanned from brains preserved with the kind of high-quality fixation that's been standard in neuroscience for many years.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

After much serious thought about neuroscience Ken has come to the conclusion that this level of physical preservation is overwhelmingly likely to capture the information necessary to restore a person in the future and I'm inclined to agree.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Again, I'll get to this in an upcoming post.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

But the electron micrographs coming from the cryonics community didn't look like what he normally saw in the lab.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

There was no 3D analysis, just single frames.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Worse, the tissue was severely dehydrated, making it difficult or impossible to tell whether the tissue was traceable, that is, whether each synapse could be traced back to its originating neurons.