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👤 PersonAppearances Over Time
Podcast Appearances
Oh, absolutely.
We tried to replicate...
in the most simplest way, what nature has come up with.
Right?
We do this by taking nitrogen, using a lot of pressure and then generating ammonia.
Life does this in a more sophisticated way, relying on one single enzyme called nitrogenase.
It's the nitrogen that is used together with eight electron donor and ATP together with a lot of hydrogen.
Life pushes this metabolism down to create fixed nitrogen.
It's quite remarkable.
So some biological engineers engineered E. coli to fix nitrogen, I believe, not us.
We use nature's nitrogen fixing bug and engineer it with the nitrogen fixing metabolism that we resurrected using our computational and phylogenetic tools.
Depends on how we define complication.
So I will start with one of the most fascinating machineries that we target, which is the translation machinery.
It is a very unique subsystem of cellular life in comparison to, I would say, metabolism.
And we used to, you know, when we are thinking about cellular life, we think of cell as the basic unit or the building block.
But from a key perspective, that's not the case.
One may argue that everything that happens inside the cell serves the translation and the translation machinery well.
There is a nice paper that called this that the entire cell is hopelessly addicted to this main informatic computing biological chemical system that is operating at the heart of the cell.
It is the translation.
converts a linear sequence of mRNA into a later folded protein.