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Betül Kaçar

👤 Speaker
1813 total appearances

Appearances Over Time

Podcast Appearances

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Enzymes are doing their thing.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

They know how to chew energy using ATP or GTP.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

They know what to do in their own way.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

They do their enzymatic thing.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So it's not just the ribosome that is at the heart of the transition, but there are a lot of different proteins.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

You're looking at about 100 different components that compose this machinery.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

You cannot have life without chemistry.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

You cannot have any cellular process without chemistry.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

What makes life interesting is that even if the chemistry is imperfect, even if there are accidents along the way, if something binds to another chemical in a way it shouldn't, there is resilience within the system that it can maybe not necessarily repair itself when it moves on.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

However, imperfect mistakes can be handled.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

That's where the biology comes in.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

But in terms of chemistry, you absolutely cannot have a translation machinery without chemistry.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And so, as I said, there are four main steps.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

These are the core steps that are conserved in all translation machinery.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And I should say, all life has this machine, right?

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Every cell, everything.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

On Earth.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yeah.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yes.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yes.