Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

Betül Kaçar

👤 Speaker
1813 total appearances

Appearances Over Time

Podcast Appearances

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

That's a very interesting and very fascinating area of study now.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And probably we will hear more about that in the decades to come.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

But if you want to go from the broad to specific, you need to understand the rules of selection.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And that is going to come from understanding biology, yes.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yeah, that was the driving question.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

We meddled with the part where you shouldn't be messing up with translation.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

You shouldn't.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

As I said, there are many ways to break it and all life needs it.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

It's, yeah, because that's how kids learn, right?

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So you have to break something and then see how it will, then you do it over and over again to see if it will fix itself in the same ways.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So it's our, I don't know, it's the most fundamental properties of ourselves as human beings.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So if we shouldn't break translation, then we should try to break it to see how it will repair.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

I broke elongation.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So we have four steps of the translations, initiate, elongate.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So you elongate the chain of the information chain that you're now creating, the peptide chain, or let's say broadly polymer chain.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And there's a termination step and there's the recycling.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So all of these steps are carried out by proteins that are also named after these steps.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Initiation is the initiation factor protein, elongation is the elongator protein.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

We broke elongation.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So the cell, the starting codon could still arrive to where it's supposed to go, but the following information couldn't get carried out because we replaced elongation with its own ancestral version.