Bliss Chapman
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Podcast Appearances
Yeah, there are actually, I mean, there's a lot of really, really interesting physics that are involved. And, you know, kind of going back to my work on ultrasound during grad school, there were groups and there are still groups looking at ways to cause neurons to actually... fire and action potential using ultrasound wave.
Yeah, there are actually, I mean, there's a lot of really, really interesting physics that are involved. And, you know, kind of going back to my work on ultrasound during grad school, there were groups and there are still groups looking at ways to cause neurons to actually... fire and action potential using ultrasound wave.
Yeah, there are actually, I mean, there's a lot of really, really interesting physics that are involved. And, you know, kind of going back to my work on ultrasound during grad school, there were groups and there are still groups looking at ways to cause neurons to actually... fire and action potential using ultrasound wave.
And the mechanism to which that's happening is still unclear as I understand. It may just be that you're imparting some sort of thermal energy and that causes cells to depolarize in some interesting ways. But there are also these ion channels or even membranes that actually just open up its pore as they're being mechanically like shook, vibrated.
And the mechanism to which that's happening is still unclear as I understand. It may just be that you're imparting some sort of thermal energy and that causes cells to depolarize in some interesting ways. But there are also these ion channels or even membranes that actually just open up its pore as they're being mechanically like shook, vibrated.
And the mechanism to which that's happening is still unclear as I understand. It may just be that you're imparting some sort of thermal energy and that causes cells to depolarize in some interesting ways. But there are also these ion channels or even membranes that actually just open up its pore as they're being mechanically like shook, vibrated.
There's just a lot of, you know, elements of these like move particles, which again, like that's governed by diffusion physics, right? Movements of particles. And there's also a lot of kind of interesting physics there.
There's just a lot of, you know, elements of these like move particles, which again, like that's governed by diffusion physics, right? Movements of particles. And there's also a lot of kind of interesting physics there.
There's just a lot of, you know, elements of these like move particles, which again, like that's governed by diffusion physics, right? Movements of particles. And there's also a lot of kind of interesting physics there.
Oh yeah, yeah. I mean, you can, yes, there's a lot of levels of physics that you can dive into. But yeah, in the end, you have these membranes with these voltage-gated ion channels that selectively let these charged molecules that are in the extracellular matrix in and out.
Oh yeah, yeah. I mean, you can, yes, there's a lot of levels of physics that you can dive into. But yeah, in the end, you have these membranes with these voltage-gated ion channels that selectively let these charged molecules that are in the extracellular matrix in and out.
Oh yeah, yeah. I mean, you can, yes, there's a lot of levels of physics that you can dive into. But yeah, in the end, you have these membranes with these voltage-gated ion channels that selectively let these charged molecules that are in the extracellular matrix in and out.
And these neurons generally have these resting potential where there's a voltage difference between inside the cell and outside the cell. And when there's some sort of... stimuli that changes the state such that they need to send information to the downstream network. You start to see these orchestration of these different molecules going in and out of these channels.
And these neurons generally have these resting potential where there's a voltage difference between inside the cell and outside the cell. And when there's some sort of... stimuli that changes the state such that they need to send information to the downstream network. You start to see these orchestration of these different molecules going in and out of these channels.
And these neurons generally have these resting potential where there's a voltage difference between inside the cell and outside the cell. And when there's some sort of... stimuli that changes the state such that they need to send information to the downstream network. You start to see these orchestration of these different molecules going in and out of these channels.
They also open up, more of them open up once it reaches some threshold to a point where you have a depolarizing cell that sends an action potential. So it's just a very beautiful kind of orchestration of these molecules.
They also open up, more of them open up once it reaches some threshold to a point where you have a depolarizing cell that sends an action potential. So it's just a very beautiful kind of orchestration of these molecules.
They also open up, more of them open up once it reaches some threshold to a point where you have a depolarizing cell that sends an action potential. So it's just a very beautiful kind of orchestration of these molecules.
And what we're trying to do when we place an electrode or parking it next to a neuron is that you're trying to measure these local changes in the potential, again, mediated by the movements of the ions. And what's interesting, as I mentioned earlier, there's a lot of physics involved. And the two dominant physics for this electrical recording domain is diffusion physics and electromagnetism.
And what we're trying to do when we place an electrode or parking it next to a neuron is that you're trying to measure these local changes in the potential, again, mediated by the movements of the ions. And what's interesting, as I mentioned earlier, there's a lot of physics involved. And the two dominant physics for this electrical recording domain is diffusion physics and electromagnetism.